Difference between revisions of "Cytopathology"

Jump to navigation Jump to search

Cytopathology (view source)

Revision as of 15:13, 9 April 2012

2,497 bytes removed ,  15:13, 9 April 2012
mv gastrointestinal cytopathology to own article
(→‎Breast cytopathology: split-out GI cytopath.)
(mv gastrointestinal cytopathology to own article)
Line 561: Line 561:
*+/-Small mature lymphocytes (common).
*+/-Small mature lymphocytes (common).
*+/-Granulomas.
*+/-Granulomas.
=Gastrointestinal=
==Liver==
Normal:
*Liver cells may be binucleated.
*Hepatocytes:
**Abundant cytoplasm, central nucleus.
**Bile ductules between adjacent cells.
**+/-Yellow granular pigment (bile).
===Hepatocellular carcinoma===
{{Main|Hepatocellular carcinoma}}
Cytology:
*Clusters of liver cells surrounded by endothelial cells.<ref name=Ref_APBR679>{{Ref APBR|679}}</ref>
*+/-Nuclear atypia.
Notes:
*Low grade [[HCC]] is composed of cytologically normal appearing cells; the arrangement is what is diagnostic of malignancy.<ref name=Ref_APBR679>{{Ref APBR|679}}</ref>
Image:
*[http://www.flickr.com/photos/78147607@N00/2331529448 HCC cytology (flickr.com/euthuman)].
===Cholangiocarcinoma===
{{Main|Cholangiocarcinoma}}
Cytology:
*Looks like an adenocarcinoma:
**Eccentric nuclei, one [[nucleolus]] per cell, abundant cytoplasm, nuclear size var. cell-to-cell, irregular nuclear membrane, irregular/uneven chromatin pattern.
==Common bile duct==
Normal:
*Monolayer of small blue cells.
Notes:
*Caution is advised when calling malignancy in the setting of a stent or stones.
===Adenocarcinoma===
Features:
*Hyperchromasia.
*Pencil-shaped nuclei.
*Nuclear membrane irregularities.
Images:
*[http://commons.wikimedia.org/wiki/File:Colorectal_adenocarcinoma_cytology_low_mag.jpg Colorectal adenocarcinoma - low mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Colorectal_adenocarcinoma_cytology_intermed_mag.jpg Colorectal adenocarcinoma - intermediate mag. (WC)].
==Stomach==
*May be difficult to distinguish from pancreas ductal epithelium.<ref name=Ref_APBR680>{{Ref APBR|680 (Q23)}}</ref>
==Small bowel==
Epithelium:<ref name=Ref_APBR680>{{Ref APBR|680 (Q23)}}</ref>
*Small blue cells.
*Goblet cells - '''key feature'''.
Notes:
*May appear to be similar to stomach and pancreatic duct.<ref name=Ref_APBR680>{{Ref APBR|680 (Q23)}}</ref>
==Esophagus==
*Cytology may be done to look for candida.
**Report should comment on the presence of candida - if it is seen.
==Pancreas==
A short DDx:
*[[Ductal carcinoma of the pancreas]].
*[[Serous cystadenoma of the pancreas]].
*[[IPMN]].
*[[Mucinous cystadenoma of the pancreas]].
*[[Solid pseudopapillary neoplasm]].
===Mucinous tumours===
Features:
*Mucin.
Image:
*[http://moon.ouhsc.edu/kfung/jty1/OPAQ/PNPT/PNPT-Image/PN-NS01-01-01b.gif Mucin (ouhsc.edu)].<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/OPAQ/PNPT/PN-NS01-Ans.htm http://moon.ouhsc.edu/kfung/jty1/OPAQ/PNPT/PN-NS01-Ans.htm]. Accessed on: 22 February 2012.</ref>


=Kidney cytology=
=Kidney cytology=
Michael
48,448

edits

Retrieved from "https://librepathology.org/wiki/Special:MobileDiff/14696"

Navigation menu