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Difference between revisions of "Head and neck cytopathology"
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Thyroid cytopathology is dealt with in the ''[[thyroid cytopathology]]'' article. An introduction to cytopathology is in the ''[[cytopathology]]'' article. | Thyroid cytopathology is dealt with in the ''[[thyroid cytopathology]]'' article. An introduction to cytopathology is in the ''[[cytopathology]]'' article. | ||
=Normal= | |||
Depends on the structure that is needled. | Depends on the structure that is needled. | ||
| Line 18: | Line 18: | ||
*Irregular globs of tissue with small cells. | *Irregular globs of tissue with small cells. | ||
=Salivary gland tumours - summary= | |||
===Benign=== | ===Benign=== | ||
{| class="wikitable" | {| class="wikitable" | ||
| Line 84: | Line 84: | ||
|} | |} | ||
=Salivary gland= | |||
{{Main|Salivary gland}} | |||
==Pleomorphic adenoma== | ==Pleomorphic adenoma== | ||
General: | General: | ||
| Line 107: | Line 109: | ||
==Warthin tumour== | ==Warthin tumour== | ||
*AKA ''papillary cystadenoma lymphomatosum''. | *AKA ''papillary cystadenoma lymphomatosum''. | ||
===General=== | |||
*Usual smokers. | |||
*May be bilateral. | |||
=== | ===Cytology=== | ||
Features:<ref>[http://sciencelinks.jp/j-east/article/200123/000020012301A0753392.php http://sciencelinks.jp/j-east/article/200123/000020012301A0753392.php]</ref> | Features:<ref>[http://sciencelinks.jp/j-east/article/200123/000020012301A0753392.php http://sciencelinks.jp/j-east/article/200123/000020012301A0753392.php]</ref> | ||
*Oncocytes. | *Oncocytes. | ||
| Line 125: | Line 130: | ||
DDx: | DDx: | ||
*Acinic cell carcinoma. | *[[Acinic cell carcinoma]]. | ||
**Spacing of tumour in AcCC is more irregular and appear more crowded. | **Spacing of tumour in AcCC is more irregular and appear more crowded. | ||
**The cell borders in AcCC is less obvious. | **The cell borders in AcCC is less obvious. | ||
*Oncocytoma | *Oncocytoma. | ||
**Oncocytoma (vis-a-vis Warthin tumour) has more '''c'''ells, more '''c'''ytoplasm, more granularity of '''c'''ytoplasm, more '''c'''omplex architecture.<ref name=boerner2003/> | **Oncocytoma (vis-a-vis [[Warthin tumour]]) has more '''c'''ells, more '''c'''ytoplasm, more granularity of '''c'''ytoplasm, more '''c'''omplex architecture.<ref name=boerner2003/> | ||
==Oncocytoma== | ==Oncocytoma== | ||
*May be confused with Warthin tumour. | ===General=== | ||
*May be confused with [[Warthin tumour]]. | |||
===Cytology=== | |||
Features: | Features: | ||
*Oncocytes. | *Oncocytes. | ||
| Line 149: | Line 156: | ||
==Mucoepidermoid carcinoma== | ==Mucoepidermoid carcinoma== | ||
{{Main|Mucoepidermoid carcinoma}} | {{Main|Mucoepidermoid carcinoma}} | ||
===Cytology=== | |||
Features: | Features: | ||
*Sheets of cells. | *Sheets of cells. | ||
| Line 162: | Line 171: | ||
==Acinic cell carcinoma== | ==Acinic cell carcinoma== | ||
{{Main|Acinic cell carcinoma}} | |||
===General=== | |||
*Uncommon. | |||
===Cytology=== | |||
Features:<ref>SB. 12 January 2010.</ref> | Features:<ref>SB. 12 January 2010.</ref> | ||
*Abundant granular cytoplasm. | *Abundant granular cytoplasm. | ||
| Line 180: | Line 194: | ||
==Adenoid cystic carcinoma== | ==Adenoid cystic carcinoma== | ||
===General=== | |||
*Usu. distinctive. | |||
===Cytology=== | |||
Features: | Features: | ||
*Solid circular islands that are well-circumscribed. | *Solid circular islands that are well-circumscribed. | ||
| Line 197: | Line 215: | ||
*[http://commons.wikimedia.org/wiki/File:Adenoid_cystic_carcinoma_cytology.jpg Adenoid cystic carcinoma -cytology (WC)]. | *[http://commons.wikimedia.org/wiki/File:Adenoid_cystic_carcinoma_cytology.jpg Adenoid cystic carcinoma -cytology (WC)]. | ||
=Other= | |||
==Melanoma== | ==Melanoma== | ||
{{Main|Malignant melanoma}} | {{Main|Malignant melanoma}} | ||
| Line 219: | Line 238: | ||
#*Differentiating morphologic features: adenocarcinoma - 3-D clusters of cells, no spindle-shaped cells. | #*Differentiating morphologic features: adenocarcinoma - 3-D clusters of cells, no spindle-shaped cells. | ||
=Lymph nodes= | |||
Normal: | Normal: | ||
*Mixed population of lymphoid cells. | *Mixed population of lymphoid cells. | ||
*+/-Lymphoglandular bodies. | |||
==Lymphoma== | ==Lymphoma== | ||
| Line 248: | Line 268: | ||
*[http://commons.wikimedia.org/wiki/File:Hodgkin_lymphoma_cytology_large.jpg HL (WC)]. | *[http://commons.wikimedia.org/wiki/File:Hodgkin_lymphoma_cytology_large.jpg HL (WC)]. | ||
=Cystic lesions of the neck= | |||
===General=== | ===General=== | ||
*One should never sign-out a cytology specimen as: "[[branchial cleft cyst]]" or "[[thyroglossal duct cyst]]". | *One should never sign-out a cytology specimen as: "[[branchial cleft cyst]]" or "[[thyroglossal duct cyst]]". | ||
| Line 289: | Line 309: | ||
#Poorly differentiated SCC may look like adenocarcinoma. | #Poorly differentiated SCC may look like adenocarcinoma. | ||
=See also= | |||
*[[Cytopathology]]. | *[[Cytopathology]]. | ||
*[[Thyroid]]. | *[[Thyroid]]. | ||
*[[Head and neck pathology]]. | *[[Head and neck pathology]]. | ||
=References= | |||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Cytopathology]] | [[Category:Cytopathology]] | ||