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(→Liver: +image, subdivide) |
m (→Malignant melanoma: w) |
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#The classic appearance of melanoma without pigment is closest to adenocarcinoma (which may have red nucleoli, large cells, abundant cytoplasm, occasional binucleation). | #The classic appearance of melanoma without pigment is closest to adenocarcinoma (which may have red nucleoli, large cells, abundant cytoplasm, occasional binucleation). | ||
#*Differentiating morphologic features: adenocarcinoma - 3-D clusters of cells, no spindle-shaped cells. | #*Differentiating morphologic features: adenocarcinoma - 3-D clusters of cells, no spindle-shaped cells. | ||
#Bug-eyed monster cells - may vaguely resemble | #Bug-eyed monster cells - may vaguely resemble Reed-Sternberg cells (RSCs) which are diagnostic of [[Hodgkin's lymphoma]] (HL). | ||
#*RSCs do not have the granular cytoplasm typical of melanoma. | #*RSCs do not have the granular cytoplasm typical of melanoma. | ||
#*Nuclei usually adjacent, i.e. not at opposite poles of the cell. | #*Nuclei usually adjacent, i.e. not at opposite poles of the cell. |
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