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Difference between revisions of "Colorectal tumours"
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→Microscopic: tweak
m (→Molecular) |
(→Microscopic: tweak) |
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**Chromatin clearing or granularity. | **Chromatin clearing or granularity. | ||
*+/-Necrosis. | *+/-Necrosis. | ||
*Architecture: | *Architecture - important for grading: | ||
**Glands | **Glands. | ||
**Sheets | **Sheets. | ||
Images: | Images: | ||
*[http://www.flickr.com/photos/euthman/2480926690/in/set-72057594114099781 Colorectal adenocarcinoma (flickr.com/euthman)]. | *[http://www.flickr.com/photos/euthman/2480926690/in/set-72057594114099781 Colorectal adenocarcinoma (flickr.com/euthman)]. | ||
*[http://commons.wikimedia.org/wiki/File:Adenocarcinoma_coli.jpg Colorectal adenocarcinoma (WC)]. | *[http://commons.wikimedia.org/wiki/File:Adenocarcinoma_coli.jpg Colorectal adenocarcinoma (WC)]. | ||
====Grading==== | |||
Based on component composed of glands: | |||
*>=50% of tumour = low-grade (''well-differentiated'' and ''moderately differentiated''). | |||
*<50% of tumour = high-grade (''poorly-differentiated'' and ''undifferentiated''). | |||
===IHC=== | ===IHC=== | ||