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Difference between revisions of "Basics"
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→Lymph node metstatsis: tweak
(→Clinician talk: tweak, promote section) |
(→Lymph node metstatsis: tweak) |
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*Subcapsular space - the first place to look for mets. | *Subcapsular space - the first place to look for mets. | ||
*Lymph node metstasis are usually obvious. | *Lymph node metstasis are usually obvious. | ||
*Histiocytes may be difficult to separate from tumour - especially | **There are of course exceptions, e.g. [[small cell carcinoma]], [[invasive lobular carcinoma]]. | ||
**Histiocytes | *Histiocytes may be difficult to separate from tumour - especially for the novice. | ||
**Histiocytes may be found in the germinal centres, i.e. the node architecture helps. | |||
**Malignant cells, generally, have to have malignant features, i.e. the [[NC ratio]] is abnormal, there is [[nuclear pleomorphism]]. | **Malignant cells, generally, have to have malignant features, i.e. the [[NC ratio]] is abnormal, there is [[nuclear pleomorphism]]. | ||
*Several things can mimic metastases - see ''[[Lymph node metastasis]]''. | *Several things can mimic metastases - see ''[[Lymph node metastasis]]''. | ||