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Difference between revisions of "Hodgkin lymphoma"
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m
→Microscopic
m (→Classical HL: more) |
m (→Microscopic) |
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Notes: | Notes: | ||
*Large mononuclear cells are common (so called "mononuclear RSCs") but not diagnostic. | *Large mononuclear cells are common (so called "mononuclear RSCs") but not diagnostic. | ||
Images (classic HL): | Images (classic HL): | ||
| Line 71: | Line 67: | ||
**Lobulated nucleus - '''key feature'''. | **Lobulated nucleus - '''key feature'''. | ||
**Small nucleoli. | **Small nucleoli. | ||
*Subtle nodularity at low power (2.5x or 5x objective). | |||
Images (NLPHL): | Images (NLPHL): | ||
*[http://webpathology.com/image.asp?case=388&n=16 Popcorn cell (webpathology.com)]. | *[http://webpathology.com/image.asp?case=388&n=16 Popcorn cell (webpathology.com)]. | ||
*[http://commons.wikimedia.org/wiki/File:Popcorn_cell_in_nodular_lymphocyte_predominant_Hodgkin_lymphoma_-_very_high_mag_cropped.jpg Popcorn cell (WC)]. | *[http://commons.wikimedia.org/wiki/File:Popcorn_cell_in_nodular_lymphocyte_predominant_Hodgkin_lymphoma_-_very_high_mag_cropped.jpg Popcorn cell (WC)]. | ||
===DDx both CHL & NLPHL=== | |||
*CHL/NLPHL. | |||
*[[Diffuse large B cell lymphoma]] (DLBCL). | |||
*[[Anaplastic large cell lymphoma]] (ALCL). | |||
==IHC== | ==IHC== | ||