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Difference between revisions of "Liver pathology"
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→Steatosis of the liver: tweak -- loc. of steatosis
(→Steatosis of the liver: tweak -- loc. of steatosis) |
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**Histologically, these cells look like adipocytes. | **Histologically, these cells look like adipocytes. | ||
**Lipid-laden hepatocytes have gene activations suggestive of adipogenic-like transformation.<ref>URL: [http://www.jci.org/articles/view/20513/version/1 http://www.jci.org/articles/view/20513/version/1]. Accessed on: 23 September 2009.</ref> | **Lipid-laden hepatocytes have gene activations suggestive of adipogenic-like transformation.<ref>URL: [http://www.jci.org/articles/view/20513/version/1 http://www.jci.org/articles/view/20513/version/1]. Accessed on: 23 September 2009.</ref> | ||
====Microvesicular steatosis==== | ====Microvesicular steatosis==== | ||
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Notes: | Notes: | ||
*HCV genotype 3 is reported to cause periportal steatosis.<ref name=pmid16614743>Yoon EJ, Hu KQ. Hepatitis C virus (HCV) infection and hepatic steatosis. Int J Med Sci. 2006;3(2):53-6. Epub 2006 Apr 1. PMID 16614743. Avialable at: [http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1415843 http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1415843]. Accessed on: September 9, 2009.</ref> | *HCV genotype 3 is reported to cause periportal steatosis.<ref name=pmid16614743>Yoon EJ, Hu KQ. Hepatitis C virus (HCV) infection and hepatic steatosis. Int J Med Sci. 2006;3(2):53-6. Epub 2006 Apr 1. PMID 16614743. Avialable at: [http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1415843 http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1415843]. Accessed on: September 9, 2009.</ref> | ||
*Donor livers with more ''macrovescicular steatosis'' = worse outcome. | |||
**More than 30% means the liver is undesirable for [[Liver transplantation pathology|transplantation]].<ref>STC. 6 December 2010.</ref> | |||
Image: [http://commons.wikimedia.org/wiki/File:Periportal_hepatosteatosis_intermed_mag.jpg Periportal steatosis (WC)]. | Image: [http://commons.wikimedia.org/wiki/File:Periportal_hepatosteatosis_intermed_mag.jpg Periportal steatosis (WC)]. | ||