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Difference between revisions of "Neuroendocrine neoplasms"
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→Stomach: more
(→Stomach: more) |
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===Stomach=== | ===Stomach=== | ||
Divided into four types: | Divided into four types:<ref>URL: [http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/StomachNET_11protocol.pdf http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/StomachNET_11protocol.pdf]. Accessed on: 29 March 2012.</ref> | ||
*Type I. | *Type I. | ||
**Chronic atrophic gastritis - usually autoimmune gastritis. | **Chronic atrophic gastritis - usually autoimmune gastritis. | ||
**Hypochlorhydia. | **Hypochlorhydia. | ||
**Good prognosis. | |||
*Type II. | *Type II. | ||
**[[Zollinger-Ellison syndrome]] | **[[Zollinger-Ellison syndrome]]. | ||
***Often [[MEN 1]] - may be multifocal. | |||
**Hyperchlorhydia, pancreatic ''or'' duodenal NET secreting gastrin (gastrinoma). | **Hyperchlorhydia, pancreatic ''or'' duodenal NET secreting gastrin (gastrinoma). | ||
**Rare. | |||
**Poor prognosis. | |||
*Type III. | *Type III. | ||
**Usually solitary. | |||
**Sporadic. | |||
**Normal gastrin. | **Normal gastrin. | ||
**Aggressive. | **Aggressive behaviour if > 2.0 cm. | ||
*Type IV. | *Type IV. | ||
**Elevated gastrin due to parietal cell dysfunction. | **Elevated gastrin due to parietal cell dysfunction. | ||
**Extremely rare. | **Extremely rare. | ||
**Usually metastases at time of diagnosis. | |||
===Pancreatic=== | ===Pancreatic=== | ||