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Difference between revisions of "Nephrotic syndrome"
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→Microscopic: more
(→Microscopic: more) |
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| Line 156: | Line 156: | ||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
* | *Rigid (thickened) loop-like (glomerular) capillaries due to subepithelial immune complex deposition: | ||
**Spikes or pinholes - seen on silver stain. | **Spikes or pinholes - seen on silver stain - '''key light microscopy feature'''. | ||
**+/-Tram-tracking. | **+/-Tram-tracking - seen in advanced lesions. | ||
** | |||
Note: | |||
*Normal glomerular capillaries have a wavy wall with some undulation. | |||
*Early lesions may have an essential normal appearance on light microscopy. | |||
Lame memory device ''Oh ABCDEs'': | Lame memory device ''Oh ABCDEs'': | ||