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Difference between revisions of "Fibroblastic/myofibroblastic tumours"
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Fibroblastic/myofibroblastic tumours (view source)
Revision as of 02:39, 24 March 2012
, 02:39, 24 March 2012+proliferative myositis
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*[http://www.medicine.virginia.edu/clinical/departments/pathology/Case%20Studies/known-pathology-cases/95_4-page Proliferative fasciitis - several images (virginia.edu)]. | *[http://www.medicine.virginia.edu/clinical/departments/pathology/Case%20Studies/known-pathology-cases/95_4-page Proliferative fasciitis - several images (virginia.edu)]. | ||
*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20090721114221299 Proliferative fasciitis (surgicalpathologyatlas.com)]. | *[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20090721114221299 Proliferative fasciitis (surgicalpathologyatlas.com)]. | ||
==Proliferative myositis== | |||
===General=== | |||
*Benign. | |||
*Possible arise from pericytes.<ref name=pmid2058761/> | |||
===Microscopic=== | |||
Features:<ref name=pmid1586481>{{Cite journal | last1 = Lundgren | first1 = L. | last2 = Kindblom | first2 = LG. | last3 = Willems | first3 = J. | last4 = Falkmer | first4 = U. | last5 = Angervall | first5 = L. | title = Proliferative myositis and fasciitis. A light and electron microscopic, cytologic, DNA-cytometric and immunohistochemical study. | journal = APMIS | volume = 100 | issue = 5 | pages = 437-48 | month = May | year = 1992 | doi = | PMID = 1586481 }}</ref><ref name=pmid2058761>{{Cite journal | last1 = el-Jabbour | first1 = JN. | last2 = Bennett | first2 = MH. | last3 = Burke | first3 = MM. | last4 = Lessells | first4 = A. | last5 = O'Halloran | first5 = A. | title = Proliferative myositis. An immunohistochemical and ultrastructural study. | journal = Am J Surg Pathol | volume = 15 | issue = 7 | pages = 654-9 | month = Jul | year = 1991 | doi = | PMID = 2058761 }}</ref> | |||
*Large ganglion-like cells and spindle cells. | |||
*+/-Binucleation. | |||
===IHC=== | |||
Features:<ref name=pmid2058761/> | |||
*Vimentin +ve. | |||
*SMA +ve. | |||
*Desmin +ve/-ve. | |||
Others:<ref name=pmid2058761/> | |||
*Factor XIIIa -ve. | |||
*S100 -ve. | |||
*CAM5.2 -ve. | |||
*NSE -ve. | |||
==Elastofibroma== | ==Elastofibroma== | ||
| Line 233: | Line 255: | ||
*Beta-catenin +ve - '''important'''. | *Beta-catenin +ve - '''important'''. | ||
*SMA +ve ~50% of lesions. | *SMA +ve ~50% of lesions. | ||
==Low-grade myofibroblastic sarcoma== | ==Low-grade myofibroblastic sarcoma== | ||