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==Intestinal metaplasia== | ==Intestinal metaplasia== | ||
===General=== | |||
*Often part of surgical pathology report, e.g. "negative for intestinal metaplasia" or "intestinal metaplasia present". | |||
*May be associated with Helicobacter spp. infection -- though Helicobacter don't like intestinal type mucosa, i.e. H. pylori are not typically found in regions with intestinal metaplasia. | |||
====Significance==== | |||
*Moderate risk increase for carcinoma; risk less than for Barrett's esophagus.<ref name=pmid20203636>{{cite journal |author=Correa P, Piazuelo MB, Wilson KT |title=Pathology of gastric intestinal metaplasia: clinical implications |journal=Am. J. Gastroenterol. |volume=105 |issue=3 |pages=493–8 |year=2010 |month=March |pmid=20203636 |pmc=2895407 |doi=10.1038/ajg.2009.728 |url=}}</ref> | |||
===Microscopy=== | ===Microscopy=== | ||
*Goblet cells are present in the stomach.<ref>[http://esynopsis.uchc.edu/eAtlas/GI/1280.htm http://esynopsis.uchc.edu/eAtlas/GI/1280.htm]</ref> | Features: | ||
**With cresyl violet vacuole stains blue. | *Goblet cells are present in the stomach.<ref>URL: [http://esynopsis.uchc.edu/eAtlas/GI/1280.htm http://esynopsis.uchc.edu/eAtlas/GI/1280.htm]. Accessed on: 16 August 2010.</ref> | ||
**With cresyl violet vacuole [[stains]] blue. | |||
**With H&E vacuole may stain greyish. | **With H&E vacuole may stain greyish. | ||
==Gastric dysplasia== | ==Gastric dysplasia== |
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