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Difference between revisions of "Thyroid gland"
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*Medullary thyroid carcinoma oncocytic variant. | *Medullary thyroid carcinoma oncocytic variant. | ||
*Others. | *Others. | ||
==Minocycline associated thyroid pigmentation== | |||
*[[AKA]] ''minocycline thyroid''. | |||
===General=== | |||
*Benign pigmentation of the thyroid due to ''minocycline'', an antibiotic. | |||
===Gross=== | |||
*Black thyroid.<ref>{{Cite journal | last1 = Noble | first1 = JG. | last2 = Christmas | first2 = TJ. | last3 = Chapple | first3 = C. | last4 = Katz | first4 = D. | last5 = Milroy | first5 = EJ. | title = The black thyroid: an unusual finding during neck exploration. | journal = Postgrad Med J | volume = 65 | issue = 759 | pages = 34-5 | month = Jan | year = 1989 | doi = | PMID = 2780449 }}</ref> | |||
Images: | |||
*[http://images.rheumatology.org/viewphoto.php?albumId=89099&imageId=5231272 Pigmented thyroid gland (rheumatology.org)]. | |||
===Microscopic=== | |||
Features: | |||
*Granular yellow blobs: | |||
**Intracytoplasmic and intrafollicular. | |||
**Variable size ~0.5-4 micrometers. | |||
Notes: | |||
*Pigment described as ''lipofuscin-like''.<ref name=pmid6435454>{{Cite journal | last1 = Gordon | first1 = G. | last2 = Sparano | first2 = BM. | last3 = Kramer | first3 = AW. | last4 = Kelly | first4 = RG. | last5 = Iatropoulos | first5 = MJ. | title = Thyroid gland pigmentation and minocycline therapy. | journal = Am J Pathol | volume = 117 | issue = 1 | pages = 98-109 | month = Oct | year = 1984 | doi = | PMID = 6435454 | PMC = 1900569 }}</ref> | |||
===Stains=== | |||
*Fontana-Masson stain +ve. | |||
=See also= | =See also= | ||