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Difference between revisions of "Pancreas"
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→Chronic pancreatitis
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**Islets usu. preserved better than acini.<ref name=Ref_Klatt225>{{Ref Klatt|225}}</ref> | **Islets usu. preserved better than acini.<ref name=Ref_Klatt225>{{Ref Klatt|225}}</ref> | ||
*Intraluminal mucoprotein plugs. | *Intraluminal mucoprotein plugs. | ||
Images: | |||
*[http://path.upmc.edu/cases/case651.html Autoimmune pancreatitis / IgG4 sclerosing disease - several images (upmc.edu)]. | |||
====Adenocarcinoma vs. pancreatitis==== | ====Adenocarcinoma vs. pancreatitis==== | ||
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**Irregular ducts. | **Irregular ducts. | ||
**Random distribution of ducts/non-lobular arrangement. | **Random distribution of ducts/non-lobular arrangement. | ||
===IHC=== | ===IHC=== | ||
*IgG4 +ve plasma cells -- IgG4 sclerosing disease. | *IgG4 +ve plasma cells -- IgG4 sclerosing disease. | ||
To exclude pancreatic carcinoma:<ref name=pmid15725808>{{Cite journal | last1 = Hornick | first1 = JL. | last2 = Lauwers | first2 = GY. | last3 = Odze | first3 = RD. | title = Immunohistochemistry can help distinguish metastatic pancreatic adenocarcinomas from bile duct adenomas and hamartomas of the liver. | journal = Am J Surg Pathol | volume = 29 | issue = 3 | pages = 381-9 | month = Mar | year = 2005 | doi = | PMID = 15725808 }}</ref> (???) | |||
*p53 -ve. | |||
*Mesothelin -ve. | |||
=Cystic lesions - overview= | =Cystic lesions - overview= | ||