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Difference between revisions of "Lung tumours"
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→Malignant tumours
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The term is no longer used in the new classification.<ref name=pmid21926387>{{Cite journal | last1 = Travis | first1 = WD. | last2 = Brambilla | first2 = E. | last3 = Noguchi | first3 = M. | last4 = Nicholson | first4 = AG. | last5 = Geisinger | first5 = K. | last6 = Yatabe | first6 = Y. | last7 = Powell | first7 = CA. | last8 = Beer | first8 = D. | last9 = Riely | first9 = G. | title = International association for the study of lung cancer/American Thoracic Society/European Respiratory Society: international multidisciplinary classification of lung adenocarcinoma: executive summary. | journal = Proc Am Thorac Soc | volume = 8 | issue = 5 | pages = 381-5 | month = Sep | year = 2011 | doi = 10.1513/pats.201107-042ST | PMID = 21926387 |URL = http://iaslc.org/assets/Documents/lung-adenocarcinoma-classification.pdf }}</ref> | The term is no longer used in the new classification.<ref name=pmid21926387>{{Cite journal | last1 = Travis | first1 = WD. | last2 = Brambilla | first2 = E. | last3 = Noguchi | first3 = M. | last4 = Nicholson | first4 = AG. | last5 = Geisinger | first5 = K. | last6 = Yatabe | first6 = Y. | last7 = Powell | first7 = CA. | last8 = Beer | first8 = D. | last9 = Riely | first9 = G. | title = International association for the study of lung cancer/American Thoracic Society/European Respiratory Society: international multidisciplinary classification of lung adenocarcinoma: executive summary. | journal = Proc Am Thorac Soc | volume = 8 | issue = 5 | pages = 381-5 | month = Sep | year = 2011 | doi = 10.1513/pats.201107-042ST | PMID = 21926387 |URL = http://iaslc.org/assets/Documents/lung-adenocarcinoma-classification.pdf }}</ref> | ||
*It is now "adenocarcinoma in situ" see ''[[lung adenocarcinoma]]''. | *It is now "adenocarcinoma in situ" see ''[[lung adenocarcinoma]]''. | ||
==Squamous cell carcinoma of the lung== | |||
===General=== | |||
*Strong association with smoking. | |||
*May be treated with surgery. | |||
===Microscopic=== | |||
Features: | |||
*Central nucleus. | |||
*Dense appearing cytoplasm, usu. eosinophilic. | |||
*+/-Small nucleolus. | |||
DDx: | |||
*Metastatic [[squamous cell carcinoma]]. | |||
*[[Adenocarcinoma of the lung]]. | |||
==Small cell carcinoma of the lung== | |||
===General=== | |||
*Strong association with smoking. | |||
*Typically treated with chemotherapy. | |||
===Microscopic=== | |||
Features: | |||
*Stippled chromatin. | |||
*High NC ratio, scant basophilic cytoplasm. | |||
*Typically small cells ~2x RBC diameter. | |||
*+/-Nuclear moulding. | |||
*No nucleolus. | |||
*Necrosis. | |||
*Mitoses. | |||
DDx: | |||
*Metastatic small cell carcinoma. | |||
*[[Lymphoma]]. | |||
*[[Atypical carcinoid]]. | |||
*Other [[small round blue cell tumours]]. | |||
==Malignant mesothelioma== | ==Malignant mesothelioma== | ||