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An introduction to head and neck pathology (view source)
Revision as of 04:11, 12 August 2010
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==Keratocystic odontogenic tumour== | ==Keratocystic odontogenic tumour== | ||
===General=== | ===General=== | ||
*[[ | *Used to be known as ''odontogenic keratocyst''.<ref name=pmid18353202>{{Cite journal | last1 = Madras | first1 = J. | last2 = Lapointe | first2 = H. | title = Keratocystic odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour. | journal = J Can Dent Assoc | volume = 74 | issue = 2 | pages = 165-165h | month = Mar | year = 2008 | doi = | PMID = 18353202 }} | ||
</ref> | |||
*May be associated with ''[[nevoid basal cell carcinoma syndrome]]''. | |||
===Clinical=== | |||
Features:<ref name=pmid17928730>{{Cite journal | last1 = Habibi | first1 = A. | last2 = Saghravanian | first2 = N. | last3 = Habibi | first3 = M. | last4 = Mellati | first4 = E. | last5 = Habibi | first5 = M. | title = Keratocystic odontogenic tumor: a 10-year retrospective study of 83 cases in an Iranian population. | journal = J Oral Sci | volume = 49 | issue = 3 | pages = 229-35 | month = Sep | year = 2007 | doi = | PMID = 17928730 }}</ref> | |||
*Most common presentation: swelling. | |||
*Location: usually mandible. | |||
*May mimic ameloblastoma radiologically. | |||
===Microscopic=== | ===Microscopic=== | ||
Features: <ref>Thompson LDR. Head and neck pathology - (Foundations in diagnostic pathology). Goldblum JR, Ed.. Churchill Livingstone. 2006. ISBN 0-443-06960-3.</ref> | Features: <ref>Thompson LDR. Head and neck pathology - (Foundations in diagnostic pathology). Goldblum JR, Ed.. Churchill Livingstone. 2006. ISBN 0-443-06960-3.</ref> | ||
* | * Stratified epithelium resembling squamous epithelium -- but: | ||
** Lacks [[rete ridges]]. | ** Lacks [[rete ridges]]. | ||
** Artefactual separation of epithelium from the basement membrane. | ** Artefactual separation of epithelium from the basement membrane. | ||
DDx: | |||
*Odontogenic cyst. | |||
Images: | Images: | ||
*[http://commons.wikimedia.org/wiki/File:Keratocystic_odontogenic_tumour1.jpg KOT (WC)]. | *[http://commons.wikimedia.org/wiki/File:Keratocystic_odontogenic_tumour1.jpg KOT (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Keratocystic_odontogenic_tumour2.jpg KOT - showing artefactual separation (WC)] | *[http://commons.wikimedia.org/wiki/File:Keratocystic_odontogenic_tumour2.jpg KOT - showing artefactual separation of epithelium (WC)]. | ||
==Ameloblastoma== | ==Ameloblastoma== | ||