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Difference between revisions of "Lymphoma"
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→Enteropathy-associated T cell lymphoma
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==Enteropathy-associated T cell lymphoma== | ==Enteropathy-associated T cell lymphoma== | ||
*Abbreviated ''EATL''. | *Abbreviated ''EATL''. | ||
*[[AKA]] ''enteropathy-type T cell lymphoma'' (ETTL). | *[[AKA]] ''enteropathy-type T cell lymphoma'' (ETTL). | ||
===General=== | |||
*T cell lymphoma due to [[celiac sprue]]. | *T cell lymphoma due to [[celiac sprue]]. | ||
*Subdivided into type I and type II.<ref name=pmid21566094>{{cite journal |author=Delabie J, et al |title=Enteropathy-associated T-cell lymphoma: clinical and histological findings from the International Peripheral T-Cell Lymphoma Project|journal=Blood |volume=118|issue=148|pages= 148|year=2011|month=July}}</ref> | |||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features:<ref name=pmid21323966>PMID: 21323966.</ref> | ||
*Large ''or'' medium-sized lymphoid cells in the mucosa and submucosa. | |||
* | **Large-sized cells ~ 2x RBC diameter = type 1. | ||
**Medium sized cells ~ 1.5x RBC diameter = type 2. | |||
*Intestinal epithelium usually preserved. | |||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:Enteropathy-associated_T_cell_lymphoma_-_low_mag.jpg EATL (WC)]. | |||
===IHC=== | |||
Features - type 1:<ref name=pmid21323966/> | |||
*CD56 +ve. | |||
Features - type 2:<ref name=pmid21323966/><ref name=pmid21921780>PMID: 21921780.</ref> | |||
*CD8 -ve. | |||
*CD56 -ve. | |||
*CD30 +ve. | |||
==Angioimmunoblastic T-cell lymphoma== | ==Angioimmunoblastic T-cell lymphoma== | ||