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An introduction to gastrointestinal pathology (view source)
Revision as of 20:24, 4 February 2012
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**More goblet cells. | **More goblet cells. | ||
**More lymphocytes usually. | **More lymphocytes usually. | ||
===DDx by location=== | |||
*Lumen: | |||
**[[Giardiasis]], [[amebiasis]], [[enterobius]]. | |||
*Surface of epithelium: | |||
**[[Cryptosporidiosis]], [[intestinal spirochetes]]). | |||
*Infiltration of epithelium: | |||
**Intraepithelial lymphocytes - [[lymphocystic colitis]] & [[collagenous colitis]]. | |||
**Intraepithelial neutrophils - infection, IBD, ischemia. | |||
*Epithelial architeture: | |||
**Serration - [[SSA]], [[hyperplastic polyp]]. | |||
**Increased lamina propria/loss of crypts - IBD, [[juvenile polyp]]). | |||
**Distortion - IBD, infection, ischemia. | |||
**Crypt branching - IBD, ischemia, chronic infection, [[SSA]]. | |||
**Back-to-back glands - malignancy, dysplasia. | |||
*Single cell infiltrates - lamina propria: | |||
**Epithelial - signet ring cell carcinoma. | |||
**Macrophages - MAI, [[TB]], [[Whipple disease]], Yersinia. | |||
*Nuclear abnormalities: | |||
**Pseudostratification - repair, dysplasia, malignancy. | |||
**Nuclear enlargement - malignancy, viral cytopathic effect. | |||
*Submucosal: | |||
**Brunner's gland - [[duodenum]]. | |||
**Fibrosis - IBD, prolapse. | |||
**Nests - neuroendocrine tumours. | |||
=Luminal gastroenterology= | =Luminal gastroenterology= | ||