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Difference between revisions of "Non-invasive breast carcinoma"
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Non-invasive breast carcinoma (view source)
Revision as of 04:25, 3 February 2012
, 04:25, 3 February 2012→Atypical ductal hyperplasia
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Cytologic and architectural | *Cytologic and architectural feature of low-grade DCIS. | ||
**Cell spacing ~ equal. | |||
**Lumina round. | |||
**Architecture - classically ''cribriform'' or ''solid''; may be ''micropapillary'' or ''papillary''. | |||
**Small nuclei. | |||
***Small indistinct nucleoli. | |||
*Limited extent - either:<ref>{{Ref DCHH|258}}</ref> | *Limited extent - either:<ref>{{Ref DCHH|258}}</ref> | ||
*#< Two complete ducts. | *#< Two complete ducts. | ||
*#< 2 mm. | *#< 2 mm. | ||
DDx: | |||
*Low-grade [[DCIS]]. | |||
*[[Florid epithelial hyperplasia of the usual type]] (FEHUT). | |||
Note: | |||
*''High-grade DCIS'' is '''not''' in the DDx of ADH | |||
Images: | Images: | ||
*[http://commons.wikimedia.org/wiki/File:Atypical_ductal_hyperplasia_-_very_low_mag.jpg ADH - very low mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Atypical_ductal_hyperplasia_-_very_low_mag.jpg ADH - very low mag. (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Atypical_ductal_hyperplasia_-_high_mag.jpg ADH - high mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Atypical_ductal_hyperplasia_-_high_mag.jpg ADH - high mag. (WC)]. | ||
===IHC=== | |||
*CK5 <20% +ve. | |||
*ER +ve -- diffuse. | |||
==Ductal carcinoma in situ== | ==Ductal carcinoma in situ== | ||