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Difference between revisions of "Stomach"
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→Gastric lymphoma
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==Gastric lymphoma== | ==Gastric lymphoma== | ||
{{main|Lymphoma}} | |||
===General=== | |||
*MALT lymphoma = mucosa-associated lymphoid tissue lymphoma. | *MALT lymphoma = mucosa-associated lymphoid tissue lymphoma. | ||
*Associated with helicobacter infection.<ref name=pmid19273142>{{Cite journal | last1 = Mbulaiteye | first1 = SM. | last2 = Hisada | first2 = M. | last3 = El-Omar | first3 = EM. | title = Helicobacter Pylori associated global gastric cancer burden. | journal = Front Biosci | volume = 14 | issue = | pages = 1490-504 | month = | year = 2009 | doi = | PMID = 19273142 }} | *Associated with helicobacter infection.<ref name=pmid19273142>{{Cite journal | last1 = Mbulaiteye | first1 = SM. | last2 = Hisada | first2 = M. | last3 = El-Omar | first3 = EM. | title = Helicobacter Pylori associated global gastric cancer burden. | journal = Front Biosci | volume = 14 | issue = | pages = 1490-504 | month = | year = 2009 | doi = | PMID = 19273142 }} | ||
</ref> | </ref> | ||
=== | ===Microscopic=== | ||
*"Lymphoepithelial lesion" | Features: | ||
*"Lymphoepithelial lesion": | |||
**Gastric crypts invaded by a monomorphous population of lymphocytes. | |||
===IHC - work-up=== | ===IHC - work-up=== | ||
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*Triple therapy (two antibiotics, proton pump inhibitor (PPI)).<ref name=pmid19532131>{{Cite journal | last1 = Zullo | first1 = A. | last2 = Hassan | first2 = C. | last3 = Andriani | first3 = A. | last4 = Cristofari | first4 = F. | last5 = De Francesco | first5 = V. | last6 = Ierardi | first6 = E. | last7 = Tomao | first7 = S. | last8 = Morini | first8 = S. | last9 = Vaira | first9 = D. | title = Eradication therapy for Helicobacter pylori in patients with gastric MALT lymphoma: a pooled data analysis. | journal = Am J Gastroenterol | volume = 104 | issue = 8 | pages = 1932-7; quiz 1938 | month = Aug | year = 2009 | doi = 10.1038/ajg.2009.314 | PMID = 19532131 }}</ref> | *Triple therapy (two antibiotics, proton pump inhibitor (PPI)).<ref name=pmid19532131>{{Cite journal | last1 = Zullo | first1 = A. | last2 = Hassan | first2 = C. | last3 = Andriani | first3 = A. | last4 = Cristofari | first4 = F. | last5 = De Francesco | first5 = V. | last6 = Ierardi | first6 = E. | last7 = Tomao | first7 = S. | last8 = Morini | first8 = S. | last9 = Vaira | first9 = D. | title = Eradication therapy for Helicobacter pylori in patients with gastric MALT lymphoma: a pooled data analysis. | journal = Am J Gastroenterol | volume = 104 | issue = 8 | pages = 1932-7; quiz 1938 | month = Aug | year = 2009 | doi = 10.1038/ajg.2009.314 | PMID = 19532131 }}</ref> | ||
*Surgery - if triple therapy fails. | *Surgery - if triple therapy fails. | ||
Review paper: PMID 16950858. | |||
==Gastric adenocarcinoma== | ==Gastric adenocarcinoma== | ||