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Difference between revisions of "Lymphoma"
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→Angioimmunoblastic T-cell lymphoma: expand
(→Microscopic: +images) |
(→Angioimmunoblastic T-cell lymphoma: expand) |
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==Angioimmunoblastic T-cell lymphoma== | ==Angioimmunoblastic T-cell lymphoma== | ||
*Abbreviated AITL | |||
===General=== | |||
*Rare. | |||
**Common among T-cell lymphomas. | |||
*Middle age ''or'' elderly. | |||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Clear cytoplasm. | *Intermediate size cells with: | ||
**Clear/vesicular nuclei. | |||
**Moderate cytoplasm. | |||
*"Empty" sinus; subcapsular sinuses "open". | *"Empty" sinus; subcapsular sinuses "open". | ||
Images: | |||
*[http://path.upmc.edu/cases/case650.html AITL - several images (upmc.edu)] | |||
===IHC=== | ===IHC=== | ||
*CD4 +ve and CD8 +ve with CD4>CD8. | |||
*CD7 -ve. | *CD7 -ve. | ||
*CD20 +ve. | *CD20 +ve. | ||
*TIA-1 -ve. | *TIA-1 -ve. | ||
*CD21 +ve -- prominent FDC meshworks;<ref>URL: [http://path.upmc.edu/cases/case650/dx.html http://path.upmc.edu/cases/case650/dx.html]. Accessed on: 27 January 2012.</ref> tumour cell not +ve. | |||
==Primary mediastinal B-cell lymphoma== | ==Primary mediastinal B-cell lymphoma== | ||