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Difference between revisions of "Haematopathology"
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→Plasmacytoma: more
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*Malignancy derived from the plasma cells. | *Malignancy derived from the plasma cells. | ||
*Histologic component of ''multiple myeloma''; to diagnose multiple myeloma other (non-pathology) criteria are needed. | *Histologic component of ''multiple myeloma''; to diagnose multiple myeloma other (non-pathology) criteria are needed. | ||
*Prognosis: poor. | |||
===Microscopic=== | ===Microscopic=== | ||
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*Russell bodies: | *Russell bodies: | ||
**Eosinophilic, large (10-15 micrometres), homogenous immunoglobulin-containing inclusions. | **Eosinophilic, large (10-15 micrometres), homogenous immunoglobulin-containing inclusions. | ||
***Images: [http://www.healthsystem.virginia.edu/internet/hematology/hessimages/russell-bodies-website-arrow.jpg | ***Images: [http://commons.wikimedia.org/wiki/File:Russell_bodies_2_high_mag_mini.jpg Russell bodies (WC)], [http://www.healthsystem.virginia.edu/internet/hematology/hessimages/russell-bodies-website-arrow.jpg Russell bodies (healthsystem.virginia.edu)], [http://www.pathguy.com/lectures/russ2.jpg Russell bodies - several in one cell (pathguy.com)]. | ||
*Dutcher bodies - intranuclear crystalline rods. | *Dutcher bodies - intranuclear crystalline rods. | ||
**Image [http://ashimagebank.hematologylibrary.org/cgi/content/full/2003/0227/100629 Dutcher bodies (hematologylibrary.org)]. | |||
*Prominent ''perinuclear hof'' - cresent shaped lucency at the nuclear membrane (due to large Golgi apparatus). | *Prominent ''perinuclear hof'' - cresent shaped lucency at the nuclear membrane (due to large Golgi apparatus). | ||
Images: [http://ashimagebank.hematologylibrary.org/cgi/content/full/2004/0126/100984 | Images: [http://ashimagebank.hematologylibrary.org/cgi/content/full/2004/0126/100984 Various images (hematologylibrary.org)]. | ||
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