Difference between revisions of "Lymph node pathology"

Lymph node pathology (view source)

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 ===Classification===
-CD is grouped by location/involvment:
+CD is grouped by histologic appearance:<ref name=Ref_ILNP228>{{Ref ILNP|228}}</ref>
-*Hyaline vascular variant.
+#Hyaline vascular (HV) variant (described by Castleman).
-**Usually unicentric.
+#*Usually unicentric.
-**Typically mediastinal or axial.
+#*Typically mediastinal or axial.
-*Plasma cell variant.
+#*More common than plasma cell variant; represents 80-90% of CD cases.
-**Usually multicentric.
+#Plasma cell (PC) variant.
-**Abundant plasma cells.
+#*Usually multicentric, may be unicentric.
-**Associated with HHV-8 infection (the same virus implicated in ''Kaposi's sarcoma'').
+#*Abundant plasma cells.
+#*Associated with HHV-8 infection (the same virus implicated in ''Kaposi's sarcoma'').
 Discussed here: <ref name=pmid19546611>PMID 19546611</ref>