Difference between revisions of "Lymph node pathology"

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==Dermatopathic lymphadenopathy==
==Dermatopathic lymphadenopathy==
===General===
===General===
*Lymphadenopathy associated with a skin lesion. (???)
*Lymphadenopathy associated with a skin lesion - '''key feature'''.
*May be benign of malignant (e.g. T-cell lymphoma).
*May be benign or malignant (e.g. T-cell lymphoma).


===Microscopic===
===Microscopic===
*May see melanin pigment. (???)
Features:<ref name=ILNP226>{{Ref ILNP|226}}</ref>
*Abundant histiocytes & "special" cells - '''key feature''':
**Histiocytes +/- melanin pigment '''key feature''' if present.
**Interdigitating dendritic cells.
**Langerhans cells.
*+/-Plasma cells.
*+/-Eosinophils.
 
IHC:
*Interdigitating dendritic cells: S100 +ve, CD1a -ve.
*Langerhans cells: S100 +ve, CD1a +ve.


==See also==
==See also==
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