Difference between revisions of "Liver neoplasms"

Types:<ref>STC. S.30-37, 19 Jan 2009.</ref>

Types:<ref>STC. S.30-37, 19 Jan 2009.</ref>

*"Large cell dysplasia" (AKA ''large cell change'') - not considered a precursor for HCC, not considered a dysplasia.<ref name=pmid16982109>{{Cite journal  | last1 = Park | first1 = YN. | last2 = Roncalli | first2 = M. | title = Large liver cell dysplasia: a controversial entity. | journal = J Hepatol | volume = 45 | issue = 5 | pages = 734-43 | month = Nov | year = 2006 | doi = 10.1016/j.jhep.2006.08.002 | PMID = 16982109 }}</ref>

*"Large cell dysplasia" (AKA ''large cell change'') - not considered a precursor for HCC, not considered a dysplasia.<ref name=pmid16982109>{{Cite journal  | last1 = Park | first1 = YN. | last2 = Roncalli | first2 = M. | title = Large liver cell dysplasia: a controversial entity. | journal = J Hepatol | volume = 45 | issue = 5 | pages = 734-43 | month = Nov | year = 2006 | doi = 10.1016/j.jhep.2006.08.002 | PMID = 16982109 }}</ref>

*Low grade dysplasia.

*Low grade dysplasia.

*High grade dysplasia.

*High grade dysplasia.

===Neoplastic lesions===

===Neoplastic lesions===

===Malignant lesions of the liver===

===Malignant lesions of the liver===

*Hepatoblastoma - malignant liver primary in children.  

*Hepatoblastoma - malignant liver primary in children.  

*Intrahepatic cholangiocarcinoma (ICC).<ref name=pmid19212669>{{Cite journal  | last1 = Shirakawa | first1 = H. | last2 = Kuronuma | first2 = T. | last3 = Nishimura | first3 = Y. | last4 = Hasebe | first4 = T. | last5 = Nakano | first5 = M. | last6 = Gotohda | first6 = N. | last7 = Takahashi | first7 = S. | last8 = Nakagohri | first8 = T. | last9 = Konishi | first9 = M. | title = Glypican-3 is a useful diagnostic marker for a component of hepatocellular carcinoma in human liver cancer. | journal = Int J Oncol | volume = 34 | issue = 3 | pages = 649-56 | month = Mar | year = 2009 | doi =  | PMID = 19212669 | url = http://www.spandidos-publications.com/serveFile/ijo_34_3_649_PDF.pdf?type=article&article_id=ijo_34_3_649&item=PDF}}</ref>

*Intrahepatic cholangiocarcinoma (ICC).<ref name=pmid19212669>{{Cite journal  | last1 = Shirakawa | first1 = H. | last2 = Kuronuma | first2 = T. | last3 = Nishimura | first3 = Y. | last4 = Hasebe | first4 = T. | last5 = Nakano | first5 = M. | last6 = Gotohda | first6 = N. | last7 = Takahashi | first7 = S. | last8 = Nakagohri | first8 = T. | last9 = Konishi | first9 = M. | title = Glypican-3 is a useful diagnostic marker for a component of hepatocellular carcinoma in human liver cancer. | journal = Int J Oncol | volume = 34 | issue = 3 | pages = 649-56 | month = Mar | year = 2009 | doi =  | PMID = 19212669 | url = http://www.spandidos-publications.com/serveFile/ijo_34_3_649_PDF.pdf?type=article&article_id=ijo_34_3_649&item=PDF}}</ref>

Features of HCC & its precursors - generated from DCHH<ref name=Ref_DCHH170-1>{{Ref DCHH|170-1}}</ref> and STC:

Features of HCC & its precursors - generated from DCHH<ref name=Ref_DCHH170-1>{{Ref DCHH|170-1}}</ref> and STC:

{| class="wikitable"

{| class="wikitable"

|-

|-

| Plate thickness || <3 cells || <=2 cells || <=3 cells, usu. >2 cells || '''>3 cells'''

| Plate thickness || <3 cells || <=2 cells || <=3 cells, usu. >2 cells || '''>3 cells'''

|}

|}

Abbreviations:

Abbreviations:

Notes:

Notes:

*Large cell dysplasia:

*Large cell dysplasia:

**Cell size ~ 2x normal, [[NC ratio]] ~ normal.

**Cell size ~ 2x normal, [[NC ratio]] ~ normal.

**Cell size ~ 1/2x normal, NC ratio - increased.

**Cell size ~ 1/2x normal, NC ratio - increased.