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*Atypical endothelial cells - may be subtle. | *Atypical endothelial cells - may be subtle. | ||
== | ==Hepatic metastases== | ||
*[[AKA]] ''liver metastases''. | |||
===General=== | |||
*Metastases are very common - often from the gastrointestinal tract, e.g. [[colorectal cancer]]. | *Metastases are very common - often from the gastrointestinal tract, e.g. [[colorectal cancer]]. | ||
**Most liver masses in are not biopsied... as a primary lesion is evident.<ref>OA. 29 November 2009.</ref> | **Most liver masses in are not biopsied... as a primary lesion is evident.<ref>OA. 29 November 2009.</ref> | ||
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===Microscopic=== | ===Microscopic=== | ||
Features: | |||
*Histologic features are dependent on primary and degree of differentiation. | *Histologic features are dependent on primary and degree of differentiation. | ||
The classic liver metastasis ([[colorectal carcinoma]]): | The classic liver metastasis ([[colorectal carcinoma]]): | ||
*Gland forming columnar shaped cells with pseudostratified hyperchromatic cigar-shaped nuclei. | *Gland forming columnar shaped cells with pseudostratified hyperchromatic cigar-shaped nuclei. | ||
Image: | Image: | ||
*[http://commons.wikimedia.org/wiki/File:Adenocarcinoma_liver_metastasis.jpg Liver metastasis - adenocarcinoma, not obviously CRC (WC)]. | *[http://commons.wikimedia.org/wiki/File:Adenocarcinoma_liver_metastasis.jpg Liver metastasis - adenocarcinoma, not obviously CRC (WC)]. |
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