Difference between revisions of "Vasculitides"

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246 bytes added ,  16:13, 14 January 2012
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==Giant cell arteritis==
==Giant cell arteritis==
*[[AKA]] ''temporal arteritis''.
===General===
===General===
*[[AKA]] ''temporal arteritis''.
*Classically afflicts the ''temporal artery''.


===Clinical===
Clinical features:
Features:
*Classic finding: jaw claudication, in a patient older than 50 years.
*Classic finding: jaw claudication, in a patient older than 50 years.
*Other findings: headache, vision loss or diplopia, scalp tenderness, polymyalgia, weight loss, chills, fever.
*Other findings: headache, vision loss or diplopia, scalp tenderness, polymyalgia, weight loss, chills, fever.
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===Microscopic===
===Microscopic===
Features:
Features:
*Classical: [[granulomas]].
*Artery with intramural inflammatory cells.
**Classically [[granuloma|granulomatous inflammation]].
***Granulomas not required for the diagnosis!
*Destruction of arterial wall, e.g. fibrinoid necrosis (pink anucleate arterial wall).


Image(s):
Image(s):
48,474

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