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→Hepatosplenic T-cell lymphoma: more: extranodal NK/T-cell lymphoma, nasal type
(→Lymphoplasmacytic lymphoma: +IHC) |
(→Hepatosplenic T-cell lymphoma: more: extranodal NK/T-cell lymphoma, nasal type) |
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==Hepatosplenic T-cell lymphoma== | ==Hepatosplenic T-cell lymphoma== | ||
{{Main|Hepatosplenic T-cell lymphoma}} | {{Main|Hepatosplenic T-cell lymphoma}} | ||
==Extranodal NK/T-cell lymphoma, nasal type== | |||
*Abbreviated as ''ENKL'' or ''ENKTCL''. | |||
*[[AKA]] ''extranodal natural kill lymphoma'' | |||
*[[AKA]] ''angiocentric lymphoma''. | |||
===General=== | |||
*Common in east Asia.<ref name=pmid18283711>{{Cite journal | last1 = Suzuki | first1 = R. | last2 = Takeuchi | first2 = K. | last3 = Ohshima | first3 = K. | last4 = Nakamura | first4 = S. | title = Extranodal NK/T-cell lymphoma: diagnosis and treatment cues. | journal = Hematol Oncol | volume = 26 | issue = 2 | pages = 66-72 | month = Jun | year = 2008 | doi = 10.1002/hon.847 | PMID = 18283711 }}</ref> | |||
*Strong association with [[EBV]]. | |||
===Microscopic=== | |||
Features: | |||
*Atypical lymphoid cells: | |||
**[[Nucleoli]]. | |||
**[[Nuclear pleomorphism]]. | |||
**Cells centered around vessels (angiocentric). | |||
***May destroy small and medium sized arterioles. | |||
Images: | |||
*[http://path.upmc.edu/cases/case231/micro.html Extranodal NK/T-cell lymphoma, nasal type - several images (upmc.edu)]. | |||
===IHC=== | |||
Features:<ref name=pmid17064952>{{Cite journal | last1 = Al-Hakeem | first1 = DA. | last2 = Fedele | first2 = S. | last3 = Carlos | first3 = R. | last4 = Porter | first4 = S. | title = Extranodal NK/T-cell lymphoma, nasal type. | journal = Oral Oncol | volume = 43 | issue = 1 | pages = 4-14 | month = Jan | year = 2007 | doi = 10.1016/j.oraloncology.2006.03.011 | PMID = 17064952 }}</ref> | |||
*CD2 +ve. | |||
*CD3epsilon +ve (cytoplasmic). | |||
*CD56 +ve. | |||
==Table of lymphoma== | ==Table of lymphoma== | ||