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*Look like sex cord tumour:<ref>URL: [http://www.nature.com/modpathol/journal/v19/n1/full/3800475a.html http://www.nature.com/modpathol/journal/v19/n1/full/3800475a.html]. Accessed on: 5 August 2010.</ref> | *Look like sex cord tumour:<ref>URL: [http://www.nature.com/modpathol/journal/v19/n1/full/3800475a.html http://www.nature.com/modpathol/journal/v19/n1/full/3800475a.html]. Accessed on: 5 August 2010.</ref> | ||
**May have: anastomosing cords, [[trabeculae]], small nests and/or tubules. | **May have: anastomosing cords, [[trabeculae]], small nests and/or tubules. | ||
==Atypical polypoid adenomyoma of the uterus== | |||
*[[AKA]] ''atypical polypoid adenomyoma''. | |||
===General=== | |||
*Very rare.<ref name=pmid21684185>{{Cite journal | last1 = Terada | first1 = T. | title = Atypical polypoid adenomyoma of the uterus: an immunohistochemical study on 5 cases. | journal = Ann Diagn Pathol | volume = 15 | issue = 5 | pages = 338-41 | month = Oct | year = 2011 | doi = 10.1016/j.anndiagpath.2011.03.008 | PMID = 21684185 }}</ref> | |||
*Reproductive age women. | |||
===Microscopic=== | |||
Features:<ref name=pmid17050990>{{Cite journal | last1 = Jakus | first1 = S. | last2 = Edmonds | first2 = P. | last3 = Dunton | first3 = C. | last4 = Holland | first4 = G. | title = Atypical polypoid adenomyoma mimicking cervical adenocarcinoma. | journal = J Low Genit Tract Dis | volume = 6 | issue = 1 | pages = 33-8 | month = Jan | year = 2002 | doi = | PMID = 17050990 }}</ref> | |||
*Glands with irregular (non-ovoid) shapes. | |||
*Benign smooth muscle around the glands. | |||
*Squamous metaplasia - very common. | |||
*Nuclear atypia (mild). | |||
DDx: | |||
*[[Endometrioid endometrial carcinoma]]. | |||
*Endocervical adenocarcinoma. | |||
Images: | |||
*[http://www.pathologypics.com/PictView.aspx?ID=1220 APA (pathologypics.com)]. | |||
===IHC=== | |||
Features (glandular component):<ref name=pmid21684185/> | |||
*AE1/AE3 +ve. | |||
*CK7 +ve. | |||
*ER +ve. | |||
*PR +ve. | |||
Significant negative (glandular component):<ref name=pmid21684185/> | |||
*CK20 -ve. | |||
*CEA -ve. | |||
=See also= | =See also= | ||
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