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Difference between revisions of "Bone"
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→Bone marrow: tweak
(→Myositis ossificans: +images) |
(→Bone marrow: tweak) |
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**e.g. 60 year old will have 60% fatty replacement. | **e.g. 60 year old will have 60% fatty replacement. | ||
* | *One should see three cell lines:<ref>[http://emedicine.medscape.com/article/199003-overview http://emedicine.medscape.com/article/199003-overview]</ref> | ||
*#Erythroid (red cells), | |||
* | *#Myeloid (white blood cells), | ||
* | *#Megakaryocytic (platelets). | ||
* | |||
Note: Lymphocytes are considered separately and typically spared in bone marrow failure.<ref>[http://emedicine.medscape.com/article/199003-overview http://emedicine.medscape.com/article/199003-overview]</ref> | Note: Lymphocytes are considered separately and typically spared in bone marrow failure.<ref>[http://emedicine.medscape.com/article/199003-overview http://emedicine.medscape.com/article/199003-overview]</ref> | ||
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*Mature hematopoeitic cells at the centre (distant from bone). | *Mature hematopoeitic cells at the centre (distant from bone). | ||
*Immature hematopoeitic cells adjacent to the bone. | *Immature hematopoeitic cells adjacent to the bone. | ||
Note: | |||
*Immediately adjacent to the bone... is where [[follicular lymphoma]] is classically found.<ref name=pmid17284114>{{Cite journal | last1 = Iancu | first1 = D. | last2 = Hao | first2 = S. | last3 = Lin | first3 = P. | last4 = Anderson | first4 = SK. | last5 = Jorgensen | first5 = JL. | last6 = McLaughlin | first6 = P. | last7 = Medeiros | first7 = LJ. | title = Follicular lymphoma in staging bone marrow specimens: correlation of histologic findings with the results of flow cytometry immunophenotypic analysis. | journal = Arch Pathol Lab Med | volume = 131 | issue = 2 | pages = 282-7 | month = Feb | year = 2007 | doi = 10.1043/1543-2165(2007)131[282:FLISBM]2.0.CO;2 | PMID = 17284114 }}</ref> | |||
=Benign variants= | =Benign variants= | ||