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Difference between revisions of "Small cell lymphomas"
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→Microscopic: +bone marrow
(→Microscopic: +bone marrow) |
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features (lymph node): | ||
*Abundant abnormally-shaped lymphoid follicles - '''key feature''' - including some of the following: | *Abundant abnormally-shaped lymphoid follicles - '''key feature''' - including some of the following: | ||
**Non-polarized mantle zone (normal mantle zone is usu. thicker at capsular aspect). | **Non-polarized mantle zone (normal mantle zone is usu. thicker at capsular aspect). | ||
| Line 121: | Line 121: | ||
Note: | Note: | ||
*The intrafollicular component of the lymph node is compressed - follicles are often described as "kissing", as they nearly touch. | *The intrafollicular component of the lymph node is compressed - follicles are often described as "kissing", as they nearly touch. | ||
*In [[bone marrow]] specimens the neoplastic cells classically have a paratrabecular arrangement,<ref name=pmid17284114>{{Cite journal | last1 = Iancu | first1 = D. | last2 = Hao | first2 = S. | last3 = Lin | first3 = P. | last4 = Anderson | first4 = SK. | last5 = Jorgensen | first5 = JL. | last6 = McLaughlin | first6 = P. | last7 = Medeiros | first7 = LJ. | title = Follicular lymphoma in staging bone marrow specimens: correlation of histologic findings with the results of flow cytometry immunophenotypic analysis. | journal = Arch Pathol Lab Med | volume = 131 | issue = 2 | pages = 282-7 | month = Feb | year = 2007 | doi = 10.1043/1543-2165(2007)131[282:FLISBM]2.0.CO;2 | PMID = 17284114 }}</ref> i.e. the lymphoma cells are found adjacent to the bone spicules. | |||
====Grading==== | ====Grading==== | ||