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Difference between revisions of "Neuropathology"
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→Stroke: more
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==Stroke== | ==Stroke== | ||
*[[AKA]] ''cerebrovascular accident'', abbreviated ''CVA''. | |||
===General=== | |||
*Very common. | |||
*Leading cause of morbidity and mortality. | |||
Clinical classification: | |||
# Hemorrhagic stroke. | |||
# Ischemic stroke. | |||
===Gross=== | ===Gross=== | ||
*Soft/mushy brain. | *Soft/mushy brain. | ||
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***"Roof" is absent in trauma. | ***"Roof" is absent in trauma. | ||
**Cavity - in older infarcts. | **Cavity - in older infarcts. | ||
***''Multiple sclerosis'' does not cavitate. | ***''[[Multiple sclerosis]]'' does not cavitate. | ||
*Laminar necrosis = (thin) chalky line replaces grey mater.<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/neurotest/Q03-Ans.htm http://moon.ouhsc.edu/kfung/jty1/neurotest/Q03-Ans.htm]. Accessed on: 26 October 2010.</ref> | *Laminar necrosis = (thin) chalky line replaces grey mater.<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/neurotest/Q03-Ans.htm http://moon.ouhsc.edu/kfung/jty1/neurotest/Q03-Ans.htm]. Accessed on: 26 October 2010.</ref> | ||
**[[AKA]] ''pseudolaminar necrosis'' - as it is not localized to a specific layer of the cortex.<ref>MUN. 26 November 2010.</ref> | **[[AKA]] ''pseudolaminar necrosis'' - as it is not localized to a specific layer of the cortex.<ref>MUN. 26 November 2010.</ref> | ||
==Microscopic== | |||
Features: | |||
*Ischemic neurons. | |||
*+/-Neuronal loss. | |||
*+/-Microglial. | |||
*+/-[[Thrombosis]]. | |||
*+/-[[Atherosclerosis]]. | |||
==Hypoxic-ischemic encephalopathy== | ==Hypoxic-ischemic encephalopathy== | ||