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Difference between revisions of "Leukemia"
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→Leukemia classification: write-out
(→t(15;17): tweak) |
(→Leukemia classification: write-out) |
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==Leukemia classification== | ==Leukemia classification== | ||
AML: | Acute myeloid leukemia (AML): | ||
#AML. | #AML. | ||
#AML with recurrent cytogenetic abnormalities. | #AML with recurrent cytogenetic abnormalities. | ||
| Line 53: | Line 53: | ||
#AML in the setting of Down syndrome. | #AML in the setting of Down syndrome. | ||
ALL: | Acute lymphoid leukemia (ALL): | ||
#B cell. | #B cell. | ||
#B cell with recurrent cytogenetic abnormalities. | #B cell with recurrent cytogenetic abnormalities. | ||
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===AML with recurrent cytogenetic abnormalities=== | ===AML with recurrent cytogenetic abnormalities=== | ||
====t(8;21)==== | ====Acute myeloid leukemia with t(8;21)==== | ||
*t(8;21)(q22;q22).<ref>{{Cite journal | last1 = Berger | first1 = R. | title = Translocation t(8;21)(q22;q22): cytogenetics and molecular biology. | journal = Nouv Rev Fr Hematol | volume = 36 Suppl 1 | issue = | pages = S67-9 | month = | year = 1994 | doi = | PMID = 8177719 }}</ref> | *t(8;21)(q22;q22).<ref>{{Cite journal | last1 = Berger | first1 = R. | title = Translocation t(8;21)(q22;q22): cytogenetics and molecular biology. | journal = Nouv Rev Fr Hematol | volume = 36 Suppl 1 | issue = | pages = S67-9 | month = | year = 1994 | doi = | PMID = 8177719 }}</ref> | ||
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*CD19+, PAX5+, CD79a +/-. | *CD19+, PAX5+, CD79a +/-. | ||
====inv(16)==== | ====Acute myeloid leukemia with inv(16)==== | ||
*inv(16)(p13.1q22).<ref name=pmid16917916>{{Cite journal | last1 = Lu | first1 = CM. | last2 = Murata-Collins | first2 = JL. | last3 = Wang | first3 = E. | last4 = Siddiqi | first4 = I. | last5 = Lawrence | first5 = HJ. | title = Concurrent acute myeloid leukemia with inv(16)(p13.1q22) and chronic lymphocytic leukemia: molecular evidence of two separate diseases. | journal = Am J Hematol | volume = 81 | issue = 12 | pages = 963-8 | month = Dec | year = 2006 | doi = 10.1002/ajh.20716 | PMID = 16917916 }} | *inv(16)(p13.1q22).<ref name=pmid16917916>{{Cite journal | last1 = Lu | first1 = CM. | last2 = Murata-Collins | first2 = JL. | last3 = Wang | first3 = E. | last4 = Siddiqi | first4 = I. | last5 = Lawrence | first5 = HJ. | title = Concurrent acute myeloid leukemia with inv(16)(p13.1q22) and chronic lymphocytic leukemia: molecular evidence of two separate diseases. | journal = Am J Hematol | volume = 81 | issue = 12 | pages = 963-8 | month = Dec | year = 2006 | doi = 10.1002/ajh.20716 | PMID = 16917916 }} | ||
</ref> | </ref> | ||
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*CD2+ -- common. | *CD2+ -- common. | ||
====t(15;17)==== | ====Acute myeloid leukemia with t(15;17)==== | ||
*t(15;17)(q22;q12). | *t(15;17)(q22;q12). | ||
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*t(5;17). (???) | *t(5;17). (???) | ||
====t(9;11)==== | ====Acute myeloid leukemia with t(9;11)==== | ||
*t(9;11). | *t(9;11). | ||