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→Common non-neoplastic disease: create pseudomembranous colitis
(mv polyp section, tweak text, chg heading in grossing) |
(→Common non-neoplastic disease: create pseudomembranous colitis) |
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*[http://histology-group28.wikispaces.com/file/view/divertic.jpg/60992930/divertic.jpg DD (wikispaces.com)].<ref>URL: [http://histology-group28.wikispaces.com/DigestiveSystemProject http://histology-group28.wikispaces.com/DigestiveSystemProject]. Accessed on: 23 August 2011.</ref> | *[http://histology-group28.wikispaces.com/file/view/divertic.jpg/60992930/divertic.jpg DD (wikispaces.com)].<ref>URL: [http://histology-group28.wikispaces.com/DigestiveSystemProject http://histology-group28.wikispaces.com/DigestiveSystemProject]. Accessed on: 23 August 2011.</ref> | ||
==Pseudomembranous colitis== | |||
===General=== | |||
*''Pseudomembranous colitis'' is a histomorphologic description which has a [[DDx]]. In other words, it can be caused by a number of things. | |||
DDx of pseudomembranous colitis:<ref name=Ref_PBoD837-8>{{Ref PBoD|837-8}}</ref> | |||
**[[C. difficile]]. | |||
***Known as ''C. difficile colitis''. | |||
**[[Ischemic colitis]]. | |||
***Volvulus. | |||
**Other infections. | |||
Etiology: | |||
*Anything that causes a severe mucosal injury. | |||
===Gross=== | |||
*Pseudomembranes. | |||
===Microscopic=== | |||
Features:<ref name=Ref_PBoD837-8>{{Ref PBoD|837-8}}</ref> | |||
*Heaped necrosis of surface epithelium. | |||
**Described as "volanco lesions" - this is what is seen endoscopically. | |||
*[[PMN]]s in lamina propria. | |||
*+/-Capillary fibrin thrombi. | |||
Note: | |||
*Pseudomembranes arise from the crypts. | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Colonic_pseudomembranes_low_mag.jpg Micrograph of pseudomembranes - low mag. (wikimedia.org)]. | |||
*[http://commons.wikimedia.org/wiki/File:Colonic_pseudomembranes_intermed_mag.jpg Micrograph of pseudomembranes - intermed. mag. (wikimedia.org)]. | |||
=Inflammatory diseases= | =Inflammatory diseases= | ||