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Difference between revisions of "Chondro-osseous tumours"
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→Chondrosarcoma: +dediff. chondrosarc.
(→Microscopic: +images) |
(→Chondrosarcoma: +dediff. chondrosarc.) |
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*Mesenchymal chondrosarcoma. | *Mesenchymal chondrosarcoma. | ||
*Clear cell chondrosarcoma. | *Clear cell chondrosarcoma. | ||
*Dedifferentiated | *Dedifferentiated chondrosarcoma. | ||
===Microscopic=== | ===Microscopic=== | ||
| Line 320: | Line 320: | ||
Image: | Image: | ||
*[http://www.cttr.org/large/03113.jpg Extraskeletal myxoid chondrosarcoma (cttr.org)].<ref>URL: [http://www.cttr.org/cms/?p=736 http://www.cttr.org/cms/?p=736]. Accessed on: 1 May 2011.</ref> | *[http://www.cttr.org/large/03113.jpg Extraskeletal myxoid chondrosarcoma (cttr.org)].<ref>URL: [http://www.cttr.org/cms/?p=736 http://www.cttr.org/cms/?p=736]. Accessed on: 1 May 2011.</ref> | ||
=====Dedifferentiated chondrosarcoma===== | |||
Clinical: | |||
*Abysmal to poor prognosis. | |||
**In one series (22 patients) 5-year survival ~20%.<ref>{{Cite journal | last1 = Mitchell | first1 = AD. | last2 = Ayoub | first2 = K. | last3 = Mangham | first3 = DC. | last4 = Grimer | first4 = RJ. | last5 = Carter | first5 = SR. | last6 = Tillman | first6 = RM. | title = Experience in the treatment of dedifferentiated chondrosarcoma. | journal = J Bone Joint Surg Br | volume = 82 | issue = 1 | pages = 55-61 | month = Jan | year = 2000 | doi = | PMID = 10697315 | URL = http://www.jbjs.org.uk/cgi/pmidlookup?view=long&pmid=10697315 }}</ref> | |||
**All dead in two years in another series (25 patients).<ref name=pmid17653766/> | |||
Features:<ref name=pmid17653766>{{Cite journal | last1 = Sopta | first1 = J. | last2 = Dordević | first2 = A. | last3 = Tulić | first3 = G. | last4 = Mijucić | first4 = V. | title = Dedifferentiated chondrosarcoma: our clinico-pathological experience and dilemmas in 25 cases. | journal = J Cancer Res Clin Oncol | volume = 134 | issue = 2 | pages = 147-52 | month = Feb | year = 2008 | doi = 10.1007/s00432-007-0262-5 | PMID = 17653766 }}</ref> | |||
#Poorly differentiated (mesenchymal) malignancy. | |||
#Well-differentiated cartilaginous component. | |||
Images: | |||
*[http://path.upmc.edu/cases/case118/micro.html Dedifferentiated chondrosarcoma (upmc.edu)]. | |||
====Grading==== | ====Grading==== | ||