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==Prosthetic joint infection== | ==Prosthetic joint infection== | ||
===General=== | ===General=== | ||
* | *Bits of tissue come for [[frozen section]] to r/o infection. | ||
*The interface membrane (''not'' the pseudocapsule) should be sampled to obtain a high [[sensitivity]].<ref name=pmid21131917/> | |||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Neutrophils. | *Neutrophils - '''key feature'''. | ||
Various criteria exist.<ref name=pmid17545426>{{Cite journal | last1 = Bori | first1 = G. | last2 = Soriano | first2 = A. | last3 = García | first3 = S. | last4 = Mallofré | first4 = C. | last5 = Riba | first5 = J. | last6 = Mensa | first6 = J. | title = Usefulness of histological analysis for predicting the presence of microorganisms at the time of reimplantation after hip resection arthroplasty for the treatment of infection. | journal = J Bone Joint Surg Am | volume = 89 | issue = 6 | pages = 1232-7 | month = Jun | year = 2007 | doi = 10.2106/JBJS.F.00741 | PMID = 17545426 }}</ref> | Various criteria exist.<ref name=pmid17545426>{{Cite journal | last1 = Bori | first1 = G. | last2 = Soriano | first2 = A. | last3 = García | first3 = S. | last4 = Mallofré | first4 = C. | last5 = Riba | first5 = J. | last6 = Mensa | first6 = J. | title = Usefulness of histological analysis for predicting the presence of microorganisms at the time of reimplantation after hip resection arthroplasty for the treatment of infection. | journal = J Bone Joint Surg Am | volume = 89 | issue = 6 | pages = 1232-7 | month = Jun | year = 2007 | doi = 10.2106/JBJS.F.00741 | PMID = 17545426 }}</ref> | ||
* | *The definitions suffer from [[HPFitis]]. | ||
====Feldman criteria==== | ====Feldman criteria==== | ||
*>= Five neutrophils / [[HPF]] (x400) in at least five separate microscopic fields.<ref name=pmid17545426/><ref name=pmid21131917>{{Cite journal | last1 = Bori | first1 = G. | last2 = Muñoz-Mahamud | first2 = E. | last3 = Garcia | first3 = S. | last4 = Mallofre | first4 = C. | last5 = Gallart | first5 = X. | last6 = Bosch | first6 = J. | last7 = Garcia | first7 = E. | last8 = Riba | first8 = J. | last9 = Mensa | first9 = J. | title = Interface membrane is the best sample for histological study to diagnose prosthetic joint infection. | journal = Mod Pathol | volume = 24 | issue = 4 | pages = 579-84 | month = Apr | year = 2011 | doi = 10.1038/modpathol.2010.219 | PMID = 21131917 | URL = http://www.nature.com/modpathol/journal/v24/n4/full/modpathol2010219a.html }}</ref> | *>= Five neutrophils / [[HPF]] (x400) in at least five separate microscopic fields.<ref name=pmid17545426/><ref name=pmid21131917>{{Cite journal | last1 = Bori | first1 = G. | last2 = Muñoz-Mahamud | first2 = E. | last3 = Garcia | first3 = S. | last4 = Mallofre | first4 = C. | last5 = Gallart | first5 = X. | last6 = Bosch | first6 = J. | last7 = Garcia | first7 = E. | last8 = Riba | first8 = J. | last9 = Mensa | first9 = J. | title = Interface membrane is the best sample for histological study to diagnose prosthetic joint infection. | journal = Mod Pathol | volume = 24 | issue = 4 | pages = 579-84 | month = Apr | year = 2011 | doi = 10.1038/modpathol.2010.219 | PMID = 21131917 | URL = http://www.nature.com/modpathol/journal/v24/n4/full/modpathol2010219a.html }}</ref> | ||
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====Athanasou criterion==== | ====Athanasou criterion==== | ||
*>= Ten neutrophils / ten [[HPF]] (x400).<ref name=pmid17545426/> | *>= Ten neutrophils / ten [[HPF]] (x400).<ref name=pmid17545426/> | ||
==Juxta-articular myxoma== | ==Juxta-articular myxoma== |
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