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*Histiocytes may be difficult to separate from tumour - especially initially. | *Histiocytes may be difficult to separate from tumour - especially initially. | ||
**Histiocytes (usually) are in germinal centres, i.e. the node architecture helps. | **Histiocytes (usually) are in germinal centres, i.e. the node architecture helps. | ||
**Malignant cells, generally, have to have malignant features, i.e. the NC ratio is abnormal, there is [[nuclear pleomorphism]]. | **Malignant cells, generally, have to have malignant features, i.e. the [[NC ratio]] is abnormal, there is [[nuclear pleomorphism]]. | ||
*Several things can mimic metastases - see ''[[Lymph node metastasis]]''. | *Several things can mimic metastases - see ''[[Lymph node metastasis]]''. | ||
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