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Difference between revisions of "Non-malignant skin disease"
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*[http://www.flickr.com/photos/euthman/3059309003/ Inverted follicular keratosis - low mag. (flickr.com)]. | *[http://www.flickr.com/photos/euthman/3059309003/ Inverted follicular keratosis - low mag. (flickr.com)]. | ||
*[http://www.flickr.com/photos/euthman/3060145702/ Inverted follicular keratosis - high mag. (flickr.com)]. | *[http://www.flickr.com/photos/euthman/3060145702/ Inverted follicular keratosis - high mag. (flickr.com)]. | ||
==Keratoacanthoma== | |||
*Abbreviated ''KA''. | |||
*Generally considered to be benign. | |||
**Rare reports of metastases suggesting it may be a form of squamous cell carcinoma.<ref>{{cite journal |author=Mandrell JC, Santa Cruz D |title=Keratoacanthoma: hyperplasia, benign neoplasm, or a type of squamous cell carcinoma? |journal=Semin Diagn Pathol |volume=26 |issue=3 |pages=150–63 |year=2009 |month=August |pmid=20043514 |doi= |url=}}</ref> | |||
===Clinical=== | |||
*May grow rapidly (weeks or months) then involute. | |||
*Main DDx is squamous cell carcinoma. | |||
*Exophytic lesion, well-circumscribed. | |||
===Microscopic=== | |||
Features:<ref>Klatt. AOP. P. 378.</ref> | |||
*Expansion of stratum spinosum - pushing tongue-like downward growth of epidermis into the dermis. | |||
*Keratin collection (keratin plug) at the center of lesion-superficial aspect. | |||
*Cells have glassy pink cytoplasm. | |||
*Minimal/no nuclear atypia. | |||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:Skin_keratoacanthoma_whole_slide.jpg Keratocanthoma (WC).] | |||
==Bullous disease== | ==Bullous disease== | ||