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| Fruiting heads when aerobic | | Fruiting heads when aerobic | ||
| ? Immunosuppression | | ? Immunosuppression | ||
| <ref>APBR | | <ref name=Ref_APBR682>{{Ref APBR|682}}</ref> | ||
| [http://commons.wikimedia.org/w/index.php?title=File:Pulmonary_aspergillosis.jpg Aspergillus (WC)], [http://commons.wikimedia.org/wiki/File:Pulmonary_aspergillosis_cytology.jpg Aspergillus cytology (WC)] | | [http://commons.wikimedia.org/w/index.php?title=File:Pulmonary_aspergillosis.jpg Aspergillus (WC)], [http://commons.wikimedia.org/wiki/File:Pulmonary_aspergillosis_cytology.jpg Aspergillus cytology (WC)] | ||
|- | |- | ||
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| Granulomata assoc. | | Granulomata assoc. | ||
| Diabetes, immunodeficient | | Diabetes, immunodeficient | ||
| <ref>APBR | | <ref name=Ref_APBR682>{{Ref APBR|682}}</ref> | ||
| [http://granuloma.homestead.com/ZygoHE_02.jpg Mucormycosis (homestead.com)], [http://commons.wikimedia.org/wiki/File:Zygomycosis.jpg Zygomycosis (WC)] | | [http://granuloma.homestead.com/ZygoHE_02.jpg Mucormycosis (homestead.com)], [http://commons.wikimedia.org/wiki/File:Zygomycosis.jpg Zygomycosis (WC)] | ||
|- | |- | ||
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| Other? | | Other? | ||
| Immunodeficient | | Immunodeficient | ||
| <ref>APBR | | <ref name=Ref_APBR682>{{Ref APBR|682}}</ref> | ||
| [http://pathmicro.med.sc.edu/mycology/cocc3.jpg Coccidioidomycosis (med.sc.edu)] [http://commons.wikimedia.org/wiki/File:Coccidioides_immitis_on_Sabouraud%27s_medium.jpg C. immitis (WC)] | | [http://pathmicro.med.sc.edu/mycology/cocc3.jpg Coccidioidomycosis (med.sc.edu)] [http://commons.wikimedia.org/wiki/File:Coccidioides_immitis_on_Sabouraud%27s_medium.jpg C. immitis (WC)] | ||
|- | |- | ||
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| '''Intracellular (unlike candida), granulomata''' | | '''Intracellular (unlike candida), granulomata''' | ||
| Source: soil with bird droppings | | Source: soil with bird droppings | ||
| <ref>APBR | | <ref name=Ref_APBR682>{{Ref APBR|682}}</ref> | ||
| [http://commons.wikimedia.org/wiki/File:Histoplasma_pas-d.jpg Histoplasmosis (WC)] | | [http://commons.wikimedia.org/wiki/File:Histoplasma_pas-d.jpg Histoplasmosis (WC)] | ||
|- | |- | ||
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| Granulomas, '''broad-based budding yeast''' | | Granulomas, '''broad-based budding yeast''' | ||
| Habitat: Northeast America, Africa | | Habitat: Northeast America, Africa | ||
| <ref>APBR | | <ref name=Ref_APBR682>{{Ref APBR|682}}</ref><ref>[http://pathmicro.med.sc.edu/mycology/mycology-6.htm http://pathmicro.med.sc.edu/mycology/mycology-6.htm]</ref> | ||
| [http://pathmicro.med.sc.edu/mycology/blast1.jpg Blastomyces] | | [http://pathmicro.med.sc.edu/mycology/blast1.jpg Blastomyces] | ||
|- | |- | ||
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| '''Multiple budding "steering wheel" appearance''' | | '''Multiple budding "steering wheel" appearance''' | ||
| Clinical??? | | Clinical??? | ||
| <ref>APBR | | <ref name=Ref_APBR682>{{Ref APBR|682}}</ref> | ||
| [http://commons.wikimedia.org/wiki/File:Paracoccidioides_brasiliensis_01.jpg P. brasiliensis (WC)]. | | [http://commons.wikimedia.org/wiki/File:Paracoccidioides_brasiliensis_01.jpg P. brasiliensis (WC)]. | ||
|- | |- | ||
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| Usually in clusters of '''alveolar casts with a honeycomb appearance''' | | Usually in clusters of '''alveolar casts with a honeycomb appearance''' | ||
| HIV/AIDS associated | | HIV/AIDS associated | ||
| <ref>APBR | | <ref name=Ref_APBR684>{{Ref APBR|684}}</ref> | ||
| [http://commons.wikimedia.org/wiki/File:Pneumocystosis_carinii_of_lung_in_AIDS_959_lores.jpg PCP (WC)] | | [http://commons.wikimedia.org/wiki/File:Pneumocystosis_carinii_of_lung_in_AIDS_959_lores.jpg PCP (WC)] | ||
|- | |- | ||
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| '''Prominent (i.e. thick polysaccharide) capsule''' | | '''Prominent (i.e. thick polysaccharide) capsule''' | ||
| HIV/AIDS associated, most common CNS fungus | | HIV/AIDS associated, most common CNS fungus | ||
| <ref>APBR | | <ref name=Ref_APBR682>{{Ref APBR|682}}</ref> | ||
| [http://commons.wikimedia.org/wiki/File:Cryptococcosis_of_lung_in_patient_with_AIDS_Methenamine_silver_stain_963_lores.jpg Crytococcosis - methenamine silver (WC)], [http://commons.wikimedia.org/wiki/File:Cryptococcosis_of_lung_in_patient_with_AIDS._Mucicarmine_stain_962_lores.jpg Crytococcosis - mucicarmine (WC)]. | | [http://commons.wikimedia.org/wiki/File:Cryptococcosis_of_lung_in_patient_with_AIDS_Methenamine_silver_stain_963_lores.jpg Crytococcosis - methenamine silver (WC)], [http://commons.wikimedia.org/wiki/File:Cryptococcosis_of_lung_in_patient_with_AIDS._Mucicarmine_stain_962_lores.jpg Crytococcosis - mucicarmine (WC)]. | ||
|} | |} | ||
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==Cryptococcus== | ==Cryptococcus== | ||
*Usually ''C. neoformans'', fungus - opportunistic infection, typical location: lung. | *Usually ''C. neoformans'', fungus - opportunistic infection, typical location: lung. | ||
*Most common fungus seen in CSF specimens.<ref>APBR | *Most common fungus seen in CSF specimens.<ref name=Ref_APBR682>{{Ref APBR|682}}</ref> | ||
Appearance: | Appearance: | ||
*Yeast: | *Yeast: | ||
**Round/ovoid 5-15 micrometres (may resemble Histoplasma or Candida -- but often larger). | **Round/ovoid 5-15 micrometres (may resemble Histoplasma or Candida -- but often larger). | ||
**Thick mucopolysacchardie capsule + refractile centre.<ref>APBR | **Thick mucopolysacchardie capsule + refractile centre.<ref name=Ref_APBR682>{{Ref APBR|682}}</ref> | ||
**"Tear drop-shapped" budding pattern (useful to differentiate from Blastomyces, Histoplasma).<ref>APBR | **"Tear drop-shapped" budding pattern (useful to differentiate from Blastomyces, Histoplasma).<ref name=Ref_APBR682>{{Ref APBR|682}}</ref> | ||
Images: | Images: |
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