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| [[Malignant melanoma]] | | [[Malignant melanoma]] | ||
| | | spindle and/or epithelioid morphology +/-nuclear atypia (nucleoli) | ||
| mitoses (esp. deep), +/-pigment, +/-nested arch., asymmetry, upward spread (into epidermis), epithelioid m. deep | | mitoses (esp. deep), +/-pigment, +/-nested arch., asymmetry, upward spread (into epidermis), epithelioid m. deep, +/-single cells, +/-sheets of cells | ||
| ABCD = Asymmetry, Borders poor demarc., Colour dark, Diameter large | | ABCD = Asymmetry, Borders poor demarc., Colour dark, Diameter large | ||
| S100+, Melan A+, HMB-45+, microphthalmia+, tyrosinase+ | | S100+, Melan A+, HMB-45+, microphthalmia+, tyrosinase+ |
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