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Difference between revisions of "Uterine tumours"
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(→Low grade endometrial stromal sarcoma: +image) |
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==Adenosarcoma== | ==Adenosarcoma== | ||
Features:<ref>PBoD | Features:<ref name=Ref_PBoD1089>{{Ref PBoD|1089}}</ref> | ||
*Benign glands with an abnormal shape. | *Benign glands with an abnormal shape. | ||
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#*Zonal necrosis is suggestive of vascular cause. | #*Zonal necrosis is suggestive of vascular cause. | ||
#Mitoses - '''key feature'''. | #Mitoses - '''key feature'''. | ||
#*10/HPF. | #*10 mitoses/HPF. | ||
#*5/HPF - if epithelioid. | #*5 mitoses/HPF - if epithelioid. | ||
#*2/HPF - if myxoid. | #*2 mitoses/HPF - if myxoid. | ||
===IHC=== | ===IHC=== | ||
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==Smooth muscle tumour of uncertain malignant potential (STUMP)== | ==Smooth muscle tumour of uncertain malignant potential (STUMP)== | ||
*Like ''[[PUNLMP]]'' and ''[[ASCUS]]'' - a waffle category... when one isn't sure it is a ''leiomyoma'' vs. ''leiomyosarcoma''. | *Like ''[[PUNLMP]]'' and ''[[ASCUS]]'' - a waffle category... when one isn't sure it is a ''leiomyoma'' vs. ''leiomyosarcoma''. | ||
*Clinical behaviour: usually benign.<ref name=pmid19417585> | *Clinical behaviour: usually benign.<ref name=pmid19417585>{{cite journal |author=Ip PP, Cheung AN, Clement PB |title=Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases |journal=Am. J. Surg. Pathol. |volume=33 |issue=7 |pages=992–1005 |year=2009 |month=July |pmid=19417585 |doi=10.1097/PAS.0b013e3181a02d1c |url=}}</ref> | ||
*Can be subclassified into four groups - as per Stanford. | *Can be subclassified into four groups - as per Stanford. | ||
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==Endometrial stromal tumours== | ==Endometrial stromal tumours== | ||
===Overview=== | ===Overview=== | ||
WHO classification:<ref>WMSP | WHO classification:<ref name=Ref_WMSP426>{{Ref WMSP|426}}</ref> | ||
*Endometrial stromal nodule - not a tumour. | *Endometrial stromal nodule - not a tumour. | ||
*Endometrial stromal sarcoma (ESS), low grade. | *Endometrial stromal sarcoma (ESS), low grade. | ||