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===Microscopic=== | ===Microscopic=== | ||
Features to assess:<ref>{{Ref | Features to assess:<ref name=Ref_GLP46>{{Ref GLP|46}}</ref> | ||
# Lack of surface maturation. | # Lack of surface maturation. | ||
#*Lack of lighter staining at surface. | #*Lack of lighter staining at surface. | ||
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#No desmoplasia. | #No desmoplasia. | ||
#*Stromal fibrotic reaction to the tumour. | #*Stromal fibrotic reaction to the tumour. | ||
#**Desmoplasia is rare in the superficial esophagus.<ref name= | #**Desmoplasia is rare in the superficial esophagus.<ref name=Ref_GLP49>{{Ref GLP|49}}</ref> | ||
#No single cells. | #No single cells. | ||
#No extensive back-to-back glands. | #No extensive back-to-back glands. | ||
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*Changes similar to those see in colorectal tubular adenomas; however, what would be low-grade dysplasia in the rectum is high-grade dysplasia in the esophagus. | *Changes similar to those see in colorectal tubular adenomas; however, what would be low-grade dysplasia in the rectum is high-grade dysplasia in the esophagus. | ||
*Presence of goblet cells is mildly reassuring its not dysplasia.<ref>GAG. January 2009.</ref> | *Presence of goblet cells is mildly reassuring its not dysplasia.<ref>GAG. January 2009.</ref> | ||
*Desmoplasia present = invasive adenocarcinoma.<ref name= | *Desmoplasia present = invasive adenocarcinoma.<ref name=Ref_GLP54>{{Ref GLP|54}}</ref> | ||
Image: | Image: |
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