Difference between revisions of "Melanocytic lesions"

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916 bytes added ,  00:10, 11 December 2011
→‎Spitz nevus: +pigmented spindle cell nevus of Reed
(→‎Microscopic: +micrograph)
(→‎Spitz nevus: +pigmented spindle cell nevus of Reed)
Line 139: Line 139:
#*Thick collagen bundles arranged parallel to the skin surface.
#*Thick collagen bundles arranged parallel to the skin surface.
#Features of an [[intradermal nevus]].
#Features of an [[intradermal nevus]].
==Pigmented spindle cell nevus
*[[AKA]] ''pigmented spindle cell nevus of Reed''.
===General===
*Uncommon.
*Women in teens & 20s; location: shoulder, pelvic girdle region.
===Microscopic===
Features:<ref name=Ref_WMSP500>{{Ref WMSP|500}}</ref>
*Nests of heavily pigmented spindle cells at dermal-epidermal junction - '''key feature'''.
**Nevoid cells in epidermis & dermis - form "basket weave" pattern
*Well-circumscribed lesion.
Notes:
*No epithelioid nevus cells.
DDx:
*[[Spitz nevus]].
*[[Melanoma]].
Images:
*[http://commons.wikimedia.org/wiki/File:Pigmented_spindle_cell_nevus_-_low_mag.jpg PSCN - low mag. (WC)]. *[http://commons.wikimedia.org/wiki/File:Pigmented_spindle_cell_nevus_-_2_-_intermed_mag.jpg PSCN - intermed. mag. (WC)]. *[http://www.histopathology-india.net/Reed.htm Reed nevus - collection (histopathology-india.net)].


==Spitz nevus==
==Spitz nevus==
*AKA ''epithelioid and spindle-cell nevus''.
*AKA ''epithelioid and spindle-cell nevus''.


===Epidemiology===
===General===
*May be very difficult to differentiate from [[melanoma]].
 
Epidemiology:
*Children & adolescents.
*Children & adolescents.


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