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Difference between revisions of "Esophagus"
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#Nuclear changes present at surface (not only in gland crypts).<ref>GAG. January 2009.</ref> | #Nuclear changes present at surface (not only in gland crypts).<ref>GAG. January 2009.</ref> | ||
#*If changes are present at the base but ''not'' at the luminal surface -- it "matures" and is ''not'' dysplasic. | #*If changes are present at the base but ''not'' at the luminal surface -- it "matures" and is ''not'' dysplasic. | ||
# | |||
Negatives: | |||
#No desmoplasia.<ref name=Ref_GI54>{{Ref GI|54}}</ref> | |||
#*Stromal fibrotic reaction to tumour. | #*Stromal fibrotic reaction to tumour. | ||
#No architectural complexity. | |||
#*Gland dilation. | |||
#*Undulating border. | |||
#*Cribriforming. | |||
#No necrosis. | |||
Notes: | Notes: | ||
*Changes similar to those see in colorectal tubular adenomas. | *Changes similar to those see in colorectal tubular adenomas; however, what would be low-grade dysplasia in the rectum is high-grade dysplasia in the esophagus. | ||
*Presence of goblet cells is mildly reassuring its not dysplasia.<ref>GAG. January 2009.</ref> | *Presence of goblet cells is mildly reassuring its not dysplasia.<ref>GAG. January 2009.</ref> | ||
*Desmoplasia present = invasive adenocarcinoma.<ref name=Ref_GI54>{{Ref GI|54}}</ref> | *Desmoplasia present = invasive adenocarcinoma.<ref name=Ref_GI54>{{Ref GI|54}}</ref> | ||