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Difference between revisions of "Systemic lupus erythematosus"
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Systemic lupus erythematosus (view source)
Revision as of 16:56, 4 December 2011
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===Criteria=== | ===Criteria=== | ||
Mnemonic ''DAMP AS RHINO'':<ref>URL: [http://www.medicalmnemonics.com/cgi-bin/return_browse.cfm?browse=1&discipline=Rheumatology%20%2F%20Allergy http://www.medicalmnemonics.com/cgi-bin/return_browse.cfm?browse=1&discipline=Rheumatology%20%2F%20Allergy]. Accessed on: 11 September 2011.</ref> | Mnemonic ''DAMP AS RHINO'':<ref>URL: [http://www.medicalmnemonics.com/cgi-bin/return_browse.cfm?browse=1&discipline=Rheumatology%20%2F%20Allergy http://www.medicalmnemonics.com/cgi-bin/return_browse.cfm?browse=1&discipline=Rheumatology%20%2F%20Allergy]. Accessed on: 11 September 2011.</ref> | ||
* | *'''D'''iscoid rash. | ||
* | *'''A'''NA +ve | ||
* | **[[Sensitivity]] ~99%;<ref>{{Cite journal | last1 = Edworthy | first1 = SM. | last2 = Zatarain | first2 = E. | last3 = McShane | first3 = DJ. | last4 = Bloch | first4 = DA. | title = Analysis of the 1982 ARA lupus criteria data set by recursive partitioning methodology: new insights into the relative merit of individual criteria. | journal = J Rheumatol | volume = 15 | issue = 10 | pages = 1493-8 | month = Oct | year = 1988 | doi = | PMID = 3060613 }}</ref> negative finding essential excludes the diagnosis. | ||
* | *'''M'''alar rash. | ||
* | *'''P'''hotosensitive. | ||
* | *'''A'''rthritis. | ||
* | *'''S'''erositis (pericardial or pleural). | ||
* | *'''R'''enal dysfunction. | ||
* | **Proteinuria (>0.5 g/day) or cellular casts. | ||
**Anti-Smith antibody. | *'''H'''ematologic abnormality. | ||
* | **Includes: [[anemia]], leukopenia, lymphopenia, thrombocytopenia, hypocomplementemia (low C3 & C4). | ||
* | *'''I'''mmunologic abnormality. | ||
**Anti-Smith antibody, [[APLA]], VDRL false positive (test for [[syphilis]]). | |||
*'''N'''eurologic abnormality, e.g. seizures, psychosis. | |||
*'''O'''ral ulcer or nasal ulcer. | |||
===Prognosis=== | ===Prognosis=== | ||