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Difference between revisions of "Mesothelial cytopathology"
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Ref APBR
m (refs dchh) |
(Ref APBR) |
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===Peritoneal cavity specific=== | ===Peritoneal cavity specific=== | ||
*HCC may be assoc. with ascites... but it is rarely positive for malignant cells.<ref>APBR | *HCC may be assoc. with ascites... but it is rarely positive for malignant cells.<ref name=Ref_APBR679>{{Ref APBR|679}}</ref> | ||
**HCC in ascites fluid is super rare -- ''I haven't seen a case''.<ref>SB. 8 January 2010.</ref> | **HCC in ascites fluid is super rare -- ''I haven't seen a case''.<ref>SB. 8 January 2010.</ref> | ||
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==Normal mesothelium== | ==Normal mesothelium== | ||
Features:<ref>APBR | Features:<ref name=Ref_APBR674>{{Ref APBR|674}}</ref> | ||
*"Window" or "space" between attached cells (due to microvilli). | *"Window" or "space" between attached cells (due to microvilli). | ||
*Cytoplasmic blebs. | *Cytoplasmic blebs. | ||
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==Breast carcinoma in fluid== | ==Breast carcinoma in fluid== | ||
Breast adenocarcinoma in fluid - features:<ref>APBR | Breast adenocarcinoma in fluid - features:<ref name=Ref_APBR675>{{Ref APBR|675}}</ref> | ||
*Classically large morules (clusters of cells that are heaped/are "3-dimensional"), known as ''cannonballs'', with "community borders". | *Classically large morules (clusters of cells that are heaped/are "3-dimensional"), known as ''cannonballs'', with "community borders". | ||
**"Community border" = smooth, low surface area border; should be differentiated from a "knobby" border seen in mesothelioma. | **"Community border" = smooth, low surface area border; should be differentiated from a "knobby" border seen in mesothelioma. | ||
*Intracytoplasmic "lumens"/inclusions (think ''lobular carcinoma''). | *Intracytoplasmic "lumens"/inclusions (think ''lobular carcinoma''). | ||
DDx of ''cannonballs'':<ref>APBR | DDx of ''cannonballs'':<ref name=Ref_APBR675>{{Ref APBR|675}}</ref> | ||
*Breast. | *Breast. | ||
*Ovary. | *Ovary. | ||
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Features: | Features: | ||
*Cannonballs (non-specific). | *Cannonballs (non-specific). | ||
*Suggestive of CRA:<ref>APBR | *Suggestive of CRA:<ref name=Ref_APBR675>{{Ref APBR|675}}</ref> | ||
**Pseudostratified cells. | **Pseudostratified cells. | ||
**Columnar cells. | **Columnar cells. | ||