Difference between revisions of "Mesothelial cytopathology"

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Ref APBR
m (refs dchh)
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===Peritoneal cavity specific===
===Peritoneal cavity specific===
*HCC may be assoc. with ascites... but it is rarely positive for malignant cells.<ref>APBR P.679.</ref>
*HCC may be assoc. with ascites... but it is rarely positive for malignant cells.<ref name=Ref_APBR679>{{Ref APBR|679}}</ref>
**HCC in ascites fluid is super rare -- ''I haven't seen a case''.<ref>SB. 8 January 2010.</ref>
**HCC in ascites fluid is super rare -- ''I haven't seen a case''.<ref>SB. 8 January 2010.</ref>


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==Normal mesothelium==
==Normal mesothelium==
Features:<ref>APBR P.674.</ref>
Features:<ref name=Ref_APBR674>{{Ref APBR|674}}</ref>
*"Window" or "space" between attached cells (due to microvilli).
*"Window" or "space" between attached cells (due to microvilli).
*Cytoplasmic blebs.
*Cytoplasmic blebs.
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==Breast carcinoma in fluid==
==Breast carcinoma in fluid==
Breast adenocarcinoma in fluid - features:<ref>APBR P.675.</ref>
Breast adenocarcinoma in fluid - features:<ref name=Ref_APBR675>{{Ref APBR|675}}</ref>
*Classically large morules (clusters of cells that are heaped/are "3-dimensional"), known as ''cannonballs'', with "community borders".
*Classically large morules (clusters of cells that are heaped/are "3-dimensional"), known as ''cannonballs'', with "community borders".
**"Community border" = smooth, low surface area border; should be differentiated from a "knobby" border seen in mesothelioma.
**"Community border" = smooth, low surface area border; should be differentiated from a "knobby" border seen in mesothelioma.
*Intracytoplasmic "lumens"/inclusions (think ''lobular carcinoma'').
*Intracytoplasmic "lumens"/inclusions (think ''lobular carcinoma'').


DDx of ''cannonballs'':<ref>APBR P.675.</ref>
DDx of ''cannonballs'':<ref name=Ref_APBR675>{{Ref APBR|675}}</ref>
*Breast.
*Breast.
*Ovary.
*Ovary.
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Features:
Features:
*Cannonballs (non-specific).
*Cannonballs (non-specific).
*Suggestive of CRA:<ref>APBR P.675.</ref>
*Suggestive of CRA:<ref name=Ref_APBR675>{{Ref APBR|675}}</ref>
**Pseudostratified cells.
**Pseudostratified cells.
**Columnar cells.
**Columnar cells.
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