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Difference between revisions of "Duodenum"
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→Weird stuff: more, images, + gangliocytic paraganglioma
m (/* Infections of the duodenum{{cite journal |author=Serra S, Jani PA |title=An approach to duodenal biopsies |journal=J. Clin. Pathol. |volume=59 |issue=11 |pages=1133–50 |year=2006 |month=November |pmid=16679353 |pmc=1860495 |doi=10.1136/jcp.2005.) |
(→Weird stuff: more, images, + gangliocytic paraganglioma) |
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*Abnormal surface enterocytes: | *Abnormal surface enterocytes: | ||
**Focal crowding -- resembling tufts. | **Focal crowding -- resembling tufts. | ||
==Gangliocytic paraganglioma== | |||
*Abbreviated ''GP''. | |||
===General=== | |||
*Rare. | |||
*May be associated with [[neurofibromatosis type 1]].<ref name=pmid12754392>{{Cite journal | last1 = Castoldi | first1 = L. | last2 = De Rai | first2 = P. | last3 = Marini | first3 = A. | last4 = Ferrero | first4 = S. | last5 = De Luca | first5 = V. | last6 = Tiberio | first6 = G. | title = Neurofibromatosis-1 and Ampullary Gangliocytic Paraganglioma Causing Biliary and Pancreatic Obstruction. | journal = Int J Gastrointest Cancer | volume = 29 | issue = 2 | pages = 93-98 | month = | year = 2001 | doi = | PMID = 12754392 }}</ref> | |||
===Microscopic=== | |||
Features:<ref name=pmid15740625>{{Cite journal | last1 = Wong | first1 = A. | last2 = Miller | first2 = AR. | last3 = Metter | first3 = J. | last4 = Thomas | first4 = CR. | title = Locally advanced duodenal gangliocytic paraganglioma treated with adjuvant radiation therapy: case report and review of the literature. | journal = World J Surg Oncol | volume = 3 | issue = 1 | pages = 15 | month = Mar | year = 2005 | doi = 10.1186/1477-7819-3-15 | PMID = 15740625 }}</ref> | |||
*Ganglion cells - '''key feature'''. | |||
**Round large nucleus. | |||
**Prominent nucleolus. | |||
*Nests or cords of epithelioid cells. | |||
DDx:<ref name=pmid15740625/> | |||
*Poorly differentiated carcinoma. | |||
*[[Neuroendocrine tumour]]. | |||
Images: | |||
*[http://www.wjso.com/content/3/1/15/figure/F2 Epithelioid cells of a GP (wjso.com)]. | |||
*[http://www.wjso.com/content/3/1/15/figure/F4 Ganglion cell in a GP (wjso.com)]. | |||
=Tumours= | =Tumours= | ||