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Difference between revisions of "Medical kidney diseases"
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Medical kidney diseases (view source)
Revision as of 15:44, 30 November 2011
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Notes: | Notes: | ||
*Hypertensive kidneys have changes only in the afferent arteriole, i.e. the efferent arteriole is spared (see ''[[hypertension]]''). | *Hypertensive kidneys have changes only in the afferent arteriole, i.e. the efferent arteriole is spared (see ''[[hypertension]]''). | ||
====Grading==== | |||
The severity of changes can be indicated by the grade:<ref>{{Cite journal | last1 = Tervaert | first1 = TW. | last2 = Mooyaart | first2 = AL. | last3 = Amann | first3 = K. | last4 = Cohen | first4 = AH. | last5 = Cook | first5 = HT. | last6 = Drachenberg | first6 = CB. | last7 = Ferrario | first7 = F. | last8 = Fogo | first8 = AB. | last9 = Haas | first9 = M. | title = Pathologic classification of diabetic nephropathy. | journal = J Am Soc Nephrol | volume = 21 | issue = 4 | pages = 556-63 | month = Apr | year = 2010 | doi = 10.1681/ASN.2010010010 | PMID = 20167701 | URL = http://jasn.asnjournals.org/content/21/4/556.full }}</ref> | |||
{| class="wikitable sortable" | |||
! Grade | |||
! Criteria | |||
|- | |||
|Grade I | |||
| GBM thickening on EM only | |||
|- | |||
|Grade II | |||
| Mild-to-moderate mesangial expansion only on LM | |||
|- | |||
|Grade III | |||
| Glomerulus with mesangial nodules (Kimmelstiel–Wilson nodules) | |||
|- | |||
|Grade IV | |||
| Stage III + global sclerosis in >50% of glomeruli | |||
|} | |||
===IF=== | ===IF=== | ||