Sinusitis

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Sinusitis is a thing that occasionally comes to the pathologist. This article deals with nonspecific sinusitis, i.e. sinusitis without an identifiable cause.

General

Microscopic

Features:

  • Sinonasal mucosa.
    • Ciliated epithelium.
    • +/-Squamous epithelium.
    • Subepithelial glands.
  • Inflammatory cells.
    • Plasma cells - usu. predominant.
    • Lymphocytes.
  • +/-Bone.

DDx:

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MIDDLE TURBINATE, LEFT, EXCISION:
- INFLAMED SINONASAL MUCOSA AND BONE.
- NEGATIVE FOR MALIGNANCY.
LEFT SINUS TISSUE, EXCISION:
- SINONASAL MUCOSA WITH CHRONIC INFLAMMATORY CELLS (PREDOMINANTLY LYMPHOCYTES AND
  PLASMA CELLS).
- NEGATIVE FOR MALIGNANCY.

Micro

The sections show mucosa with a ciliated epithelium and bland subepithelial glands. Abundant inflammatory cells, predominantly plasma cells and lymphocytes, are present. There is a lesser amount of neutrophils. Eosinophils are not significant component of the inflammation. There is no significant nuclear atypia. Mitotic activity is not readily apparent. Benign bone is present.

See also

References

  1. Desrosiers, M.; Evans, GA.; Keith, PK.; Wright, ED.; Kaplan, A.; Bouchard, J.; Ciavarella, A.; Doyle, PW. et al. (2011). "Canadian clinical practice guidelines for acute and chronic rhinosinusitis.". Allergy Asthma Clin Immunol 7 (1): 2. doi:10.1186/1710-1492-7-2. PMID 21310056.