Glomangiopericytoma

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Glomangiopericytoma, also known as sinonasal-type hemangiopericytoma and sinonasal hemangiopericytoma,

Sinonasal hemangiopericytoma may be abbreviated SNHPC.[1]

General

Microscopic

Features:[1]

  • Short spindle cells/epithelioid cells with:
    • Bland round/oval nuclei with fine chromatin.
    • Scant cytoplasm.

Note:

  • Superficial submucosal tissue spared.

DDx:

Images

IHC

Features:[3]

  • Vimentin +ve.
  • SMA +ve.
  • MSA +ve.
  • CD31 -ve.
  • CD34 -ve.

See also

References

  1. 1.0 1.1 1.2 1.3 1.4 Brandwein-Gensler, M.; Siegal, GP. (Mar 2012). "Striking pathology gold: a singular experience with daily reverberations: sinonasal hemangiopericytoma (glomangiopericytoma) and oncogenic osteomalacia.". Head Neck Pathol 6 (1): 64-74. doi:10.1007/s12105-012-0337-8. PMID 22430770.
  2. 2.0 2.1 Arpaci, RB.; Kara, T.; Vayisoğlu, Y.; Ozgur, A.; Ozcan, C. (Jul 2012). "Sinonasal glomangiopericytoma.". J Craniofac Surg 23 (4): 1194-6. doi:10.1097/SCS.0b013e31824e6d09. PMID 22801124.
  3. 3.0 3.1 Sun, Q.; Zhang, C.; Chen, W.; He, Y. (2013). "The molecular mechanisms on glomangiopericytoma invasion.". Orphanet J Rare Dis 8: 152. doi:10.1186/1750-1172-8-152. PMID 24074285.