Seminal vesicles

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The seminal vesicles, abbreviated SV, are a pair of organs closely associated with the prostate gland that add fluid to the ejaculate. They are seen attached to radical prostatectomy specimens.

Normal seminal vesicles

General

  • Seen in radical prostatectomies and occasionally in core biopsies.
  • Very rarely a site of a primary cancer.

Gross

  • Worm-like paired organs.
  • Empty into the ejaculatory ducts (as does the vas deferens).

Microscopic

  • Fern-like architecture - epithelial component clustered closely, looks like it connects.
    • Epithelium surrounded by a thick layer of muscle (>10 cells across ~80 microns).
  • Lipofuscin (coarse cytoplasmic yellow granules approximately 1-2 micrometers) - key feature.
  • Nucleoli - common.
  • Nuclear inclusions - common.[1]

Notes:

  • The ejaculatory ducts have the same epithelium as the seminal vesicles.[2]

Images

www:

IHC

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B. PROSTATE, RIGHT MEDIAL SUPERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.
- BENIGN SEMINAL VESICLE/EJACULATORY DUCT.

Pathology

Primary seminal vesicle carcinoma

Amyloid in the seminal vesicles

See also

References

  1. URL: http://surgpathcriteria.stanford.edu/prostate/adenocarcinoma/benign-vs-carcinoma.html. Accessed on: 10 January 2013.
  2. Leroy X, Ballereau C, Villers A, et al. (April 2003). "MUC6 is a marker of seminal vesicle-ejaculatory duct epithelium and is useful for the differential diagnosis with prostate adenocarcinoma". Am. J. Surg. Pathol. 27 (4): 519–21. PMID 12657938.
  3. Itami, Y.; Nagai, Y.; Kobayashi, Y.; Shimizu, N.; Yamamoto, Y.; Minami, T.; Hayashi, T.; Nozawa, M. et al. (Jul 2012). "[A case of prostatic cancer with a low PSA level accompanied with cystic formation requiring differentiation from adenocarcinoma of the seminal vesicle].". Hinyokika Kiyo 58 (7): 349-53. PMID 22895132.
  4. 4.0 4.1 Tarján, M.; Ottlecz, I.; Tot, T. (Jan 2009). "Primary adenocarcinoma of the seminal vesicle.". Indian J Urol 25 (1): 143-5. doi:10.4103/0970-1591.45557. PMID 19468449.
  5. 5.0 5.1 5.2 5.3 Terada, T. (2011). "Monstrous epithelial cell clusters in the seminal vesicle.". Int J Clin Exp Pathol 4 (7): 727-30. PMID 22076175.